The cannabinoid receptor family currently includes twotypes: CB 1, characterized in
neuronal cells and brain, and CB 2, characterized in immune cells and tissues. CB 1 and CB …

After their discovery, the two known cannabinoid receptors, CB1 and CB2, have been the
focus of research into the cellular signalling mechanisms of cannabinoids. The initial …

Cannabinoids exert most of their effects in the central nervous system through the CB1
cannabinoid receptor. This G-protein-coupled receptor has been shown to be functionally …

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Effects of cannabinoid compounds on neurons are predominantly mediated by the CB1
cannabinoid receptor. Onset of signaling cascades in response to cannabimimetic drugs is …

Almost three decades have passed since the identification of the two specific metabotropic
receptors mediating cannabinoid pharmacology. Thereafter, many cannabinoid effects, both …

Two subtypes of cannabinoid receptors, CB 1 and CB2, have been described to date,
although future investigations may elucidate other receptors. The actions of cannabimimetic …

The CB 1 cannabinoid receptor is widely distributed in the central and peripheral nervous
system. Within the neuron, the CB 1 receptor is often localised in axon terminals, and its …

Cannabinoids exert most of their effects through the CB1 receptor. This G-protein-coupled
receptor has been shown to be functionally coupled to inhibition of adenylyl cyclase …

The CB1 and CB2 cannabinoid receptors are members of the G protein-coupled receptor
(GPCR) family that are pharmacologically well defined. However, the discovery of additional …