Presently, routine screening misses many cases of prediabetes and early type 2 diabetes
(T2D). Therefore, better biomarkers are needed for a simple and early detection of …

Amino acids have emerged as novel biomarkers for predicting type 2 diabetes (T2D), but the
epidemiologic data linking circulating amino acid profiles with T2D are sparse in Asian …

Objective Circulating branched-chain amino acids (BCAAs, isoleucine, leucine, valine) and
aromatic amino acids (AAAs, tyrosine and phenylalanine) predicted type 2 diabetes mellitus …

Context: In longitudinal studies of adults, elevated amino acid (AA) concentrations predicted
future type 2 diabetes mellitus (T2DM). Objective: The aim of the present investigation was to …

Emerging technologies allow the high-throughput profiling of metabolic status from a blood
specimen (metabolomics). We investigated whether metabolite profiles could predict the …

Type 2 diabetes (T2D) 2 is a heterogeneous condition that is characterized by increased
insulin resistance and impaired insulin secretion. A progressive disorder with an insidious …

Most studies examining the association between type 2 diabetes (T2D) and amino acids
have focused on fasting concentrations. We hypothesized that, besides fasting …

Previous studies have used indirect measures of insulin sensitivity to link circulating amino
acids with insulin resistance and identify potential biomarkers of diabetes risk. Using direct …

Aim To evaluate circulating amino acids (AA) profiles in obesity, type 2 diabetes (T2D) and
metabolic syndrome (MetS). Methods Serum AA were profiled among 200; healthy, obese …

We aimed to simultaneously examine the associations of both essential and non-essential
amino acids with both prevalent and incident type 2 diabetes in a Chinese population. A …