The microvasculature underlies the supply networks that support neuronal activity within
heterogeneous brain regions. What are common versus heterogeneous aspects of the …

We present the first evidence for vascular regulation driving fMRI signals in specific
functional brain networks. Using concurrent neuronal and vascular stimuli, we collected 30 …

An amazingly wide range of complex behavior emerges from the cerebral cortex. Much of
the information processing that leads to these behaviors is performed in neocortical circuits …

Oxygen is delivered to brain tissue by a dense network of microvessels, which actively
control cerebral blood flow (CBF) through vasodilation and contraction in response to …

Despite the key role of the capillaries in neurovascular function, a thorough characterization
of cerebral capillary network properties is currently lacking. Here, we define a range of …

Recent methodological advances in fMRI contrast and readout strategies have allowed
researchers to approach the mesoscopic spatial regime of cortical layers. This has …

As high-resolution functional magnetic resonance imaging (fMRI) and fMRI of cortical layers
become more widely used, the question how well high-resolution fMRI signals reflect the …

What is the organization of cerebral microvascular oxygenation and morphology that allows
adequate tissue oxygenation at different activity levels? We address this question in the …

Layer-dependent fMRI allows measurements of information flow in cortical circuits, as
afferent and efferent connections terminate in different cortical layers. However, it is …

Cortical neurons with similar properties are grouped in columnar structures and supplied by
matching vascular networks. The hemodynamic response to neuronal activation, however, is …