Cannabinoids in traumatic brain injury and related neuropathologies: preclinical and clinical research on endogenous, plant-derived, and synthetic compounds
Traumatic brain injury is common, and often results in debilitating consequences. Even mild
traumatic brain injury leaves approximately 20% of patients with symptoms that persist for …
traumatic brain injury leaves approximately 20% of patients with symptoms that persist for …
The therapeutic potential of the cannabinoids in neuroprotection
RI Grundy - Expert opinion on investigational drugs, 2002 - Taylor & Francis
After thousands of years of interest the last few decades have seen a huge increase in our
knowledge of the cannabinoids and their mode of action. Their potential as medical …
knowledge of the cannabinoids and their mode of action. Their potential as medical …
Cannabinoids as neuroprotective agents in traumatic brain injury
A Biegon - Current pharmaceutical design, 2004 - ingentaconnect.com
The name “Cannabinoid” applies to a large and diverse family of compounds including plant
derived, synthetic and endogenously produced chemicals, some but not all of which are …
derived, synthetic and endogenously produced chemicals, some but not all of which are …
Endocannabinoids: a promising impact for traumatic brain injury
LD Schurman, AH Lichtman - Frontiers in pharmacology, 2017 - frontiersin.org
The endogenous cannabinoid (endocannabinoid) system regulates a diverse array of
physiological processes and unsurprisingly possesses considerable potential targets for the …
physiological processes and unsurprisingly possesses considerable potential targets for the …
[HTML][HTML] Cannabinoids in neurodegenerative disorders and stroke/brain trauma: from preclinical models to clinical applications
Cannabinoids form a singular family of plant-derived compounds (phytocannabinoids),
endogenous signaling lipids (endocannabinoids), and synthetic derivatives with multiple …
endogenous signaling lipids (endocannabinoids), and synthetic derivatives with multiple …
[HTML][HTML] Cannabinoids and neuroinflammation: Therapeutic implications
BE Leonard, F Aricioglu - Journal of Affective Disorders Reports, 2023 - Elsevier
This review summarizes the pharmacological properties of tetrahydrocannabinol (THC) and
cannabidiol (CBD), cannabinoid components of several species of herbal cannabis. The …
cannabidiol (CBD), cannabinoid components of several species of herbal cannabis. The …
Cannabinoids and brain injury: therapeutic implications
R Mechoulam, D Panikashvili, E Shohami - Trends in molecular medicine, 2002 - cell.com
Mounting in vitro and in vivo data suggest that the endocannabinoids anandamide and 2-
arachidonoyl glycerol, as well as some plant and synthetic cannabinoids, have …
arachidonoyl glycerol, as well as some plant and synthetic cannabinoids, have …
Therapeutic potential of cannabinoids in CNS disease
JL Croxford - CNS drugs, 2003 - Springer
The major psychoactive constituent of Cannabis sativa, Δ 9-tetrahydrocannabinol (Δ 9-THC),
and endogenous cannabinoid ligands, such as anandamide, signal through G-protein …
and endogenous cannabinoid ligands, such as anandamide, signal through G-protein …
The endocannabinoid system as a target for the treatment of neuronal damage
J Fernández-Ruiz, C García, O Sagredo… - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Cannabinoids have been proposed as clinically promising
neuroprotective molecules, based on their capability to normalize glutamate homeostasis …
neuroprotective molecules, based on their capability to normalize glutamate homeostasis …
Toward a translational approach to targeting the endocannabinoid system in posttraumatic stress disorder: a critical review of preclinical research
Despite the lack of clinical research, marijuana and synthetic cannabinoids have been
approved to treat posttraumatic stress disorder (PTSD) in several states in the United States …
approved to treat posttraumatic stress disorder (PTSD) in several states in the United States …