Ethnopharmacological relevance Cerebral ischemia/reperfusion (I/R) injury is a major cause
of neuronal damage and death. Ginkgolide B (GB) has been shown to exhibit …

Ginkgolide B (GB) has potent neuroprotective effects against ischemia-induced brain injury
in vivo and in vitro. However, the underlying mechanisms of GB's neuroprotection remain …

Ethnopharmacological relevance Rehmannioside A is derived from Rehmannia glutinosa
Libosch, which is widely used as an important ingredient in diverse traditional Chinese …

Stroke is a highly lethal and disabling disease of the central nervous system exacerbated by
oxidative stress, inflammation, and ferroptosis. However, the blood–brain barrier makes it …

Aims To evaluate the impact of galangin treatment on cerebral ischemia-reperfusion (I/R)
injury in gerbils and to identify potential mechanisms of the protective effect of galangin on …

Abstract Ethnopharmacological relevance Angong Niuhuang Wan (AGNHW) is a
prescription from traditional Chinese medicine (TCM) that has been used for centuries to …

Background Ischemic stroke, a major cause of death and disability worldwide, results from
reduced blood flow to the brain, leading to irreversible neuronal damage. Recent evidence …

Cerebral ischaemia-reperfusion injury (CIRI) is a critical component of ischaemic stroke
pathogenesis. Ferroptosis contributes to and aggravates CIRI, whereas the P62/Kelch-like …

Alzheimer's disease (AD) is a destructive neurodegenerative disease that currently has no
effective treatment option available. Ginkgolide B (GB) is a terpene lactone derivative of …

Objective Cerebral ischemia is the most common type of neuronal injury and is
characterized by a reduction in the function and number of hippocampal neurons. Carvacrol …