Obstacles against the Marketing of Curcumin as a Drug

K Hassanzadeh, L Buccarello, J Dragotto… - International journal of …, 2020 - mdpi.com
Among the extensive public and scientific interest in the use of phytochemicals to prevent or
treat human diseases in recent years, natural compounds have been highly investigated to …

Biomedical applications and bioavailability of curcumin—An updated overview

SI Sohn, A Priya, B Balasubramaniam… - Pharmaceutics, 2021 - mdpi.com
Curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa, has been
identified as the bioactive compound responsible for numerous pharmacological activities of …

Therapeutic applications of curcumin nanoformulations

MM Yallapu, PKB Nagesh, M Jaggi, SC Chauhan - The AAPS journal, 2015 - Springer
Curcumin (diferuloylmethane) is a bioactive and major phenolic component of turmeric
derived from the rhizomes of curcuma longa linn. For centuries, curcumin has exhibited …

An update on the pharmacological usage of curcumin: has it failed in the drug discovery pipeline?

F Olotu, C Agoni, O Soremekun… - Cell Biochemistry and …, 2020 - Springer
The pharmacological propensities of curcumin have been reported in a plethora of pre-
clinical and clinical studies. However, innate attributes account for extremely low oral …

Oral bioavailability of curcumin: problems and advancements

W Liu, Y Zhai, X Heng, FY Che, W Chen… - Journal of drug …, 2016 - Taylor & Francis
Curcumin is a natural compound of Curcuma longa L. and has shown many
pharmacological activities such as anti-inflammatory, anti-oxidant in both preclinical and …

Bioavailability of curcumin: problems and promises

P Anand, AB Kunnumakkara, RA Newman… - Molecular …, 2007 - ACS Publications
Curcumin, a polyphenolic compound derived from dietary spice turmeric, possesses diverse
pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and …

Pharmacological and clinical properties of curcumin

CS Beevers, S Huang - Botanics: Targets and Therapy, 2011 - Taylor & Francis
The polyphenol natural product curcumin has been the subject of numerous studies over the
past decades, which have identified and characterized the compound's pharmacokinetic …

Improving curcumin bioavailability: Current strategies and future perspectives

R Tabanelli, S Brogi, V Calderone - Pharmaceutics, 2021 - mdpi.com
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is
also characterized by problematic drug delivery and scarce bioavailability, representing the …

Bioactivity, health benefits, and related molecular mechanisms of curcumin: Current progress, challenges, and perspectives

XY Xu, X Meng, S Li, RY Gan, Y Li, HB Li - Nutrients, 2018 - mdpi.com
Curcumin is a principal curcuminoid of turmeric (Curcuma longa), which is commonly used
as a spice in cooking and a yellow pigment in the food processing industry. Recent studies …

Traditional uses, therapeutic effects and recent advances of curcumin: a mini-review

L Slika, D Patra - Mini Reviews in Medicinal Chemistry, 2020 - ingentaconnect.com
Studies regarding the uses and biological benefits curcumin have long been paid worldwide
attention. Curcumin is a polyphenol found in the turmeric spice, which is derived from the …