Securinega alkaloids are indolizidine alkaloids extracted from the leaf and root of an Asian
plant, Securinega suffruticosa. Since its discovery in 1956 by Russian scientists, numerous …

Background Securinine is an alkaloid identified from the roots and leaves of the shrub
Flueggea suffruticosa (Pall.) Baill. The molecular structure of securinine consists of four …

Seven new Securinega alkaloids, securingines A–G (1–7), together with seven known
analogues (8–14), were isolated from the twigs of Securinega suffruticosa. Their chemical …

The Securinega alkaloids are a group of compounds isolated from the plants of Securinega,
Phyllanthus and Flueggea genera belonging to the Euphorbiaceae family. Most of these …

This review gives an account of the current knowledge on the chemical constituents,
biological activity and pharmacological properties of Securinega suffruticosa. A wide range …

New securinine analogues have been prepared by semisynthesis. Two series were
developed using either Suzuki or Sonogashira cross coupling reactions. The in vitro …

Covering: 1966 to the beginning of 2009The Securinega alkaloids are a small family of plant
metabolites with fascinating bridged tetracyclic structures and significant biological activity …

Securinega alkaloids represent a family of plant secondary metabolites known for 50 years.
Securinine (1), the most abundant and studied alkaloid of this series was isolated by …

The Securinega alkaloids feature a compact tetracyclic structural framework and can be
divided into four subclasses characterized by either a bridged [2.2. 2]‐or a [3.2. 1]‐bicyclic …

Background The Securinega-type alkaloids occur in plants belonging to Euphorbiaceae
family. One of the most widely distributed alkaloid of this group is securinine, which was …