Cell-free DNA as a diagnostic tool for human parasitic infections

KG Weerakoon, DP McManus - Trends in parasitology, 2016 - cell.com
Parasites often cause devastating diseases and represent a significant public health and
economic burden. More accurate and convenient diagnostic tools are needed in support of …

[HTML][HTML] Next generation sequencing of microbial cell-free DNA for rapid noninvasive diagnosis of infectious diseases in immunocompromised hosts

JF Camargo, A Ahmed, MI Morris, S Anjan… - Biology of Blood and …, 2019 - Elsevier
Background Cell-free DNA (cfDNA) sequencing has emerged as a novel laboratory method
for rapid and noninvasive diagnosis in prenatal screening, organ transplant rejection, and …

Impact of preanalytical and analytical methods on cell-free DNA diagnostics

J Krasic, I Abramovic, A Vrtaric… - Frontiers in cell and …, 2021 - frontiersin.org
While tissue biopsy has for the longest time been the gold-standard in biomedicine,
precision/personalized medicine is making the shift toward liquid biopsies. Cell-free DNA …

Cell-free DNA: applications in different diseases

R Ranucci - Cell-free DNA as Diagnostic Markers: Methods and …, 2019 - Springer
Since its discovery in human blood plasma about 70 years ago, circulating cell-free DNA
(cfDNA) has become an attractive subject of research as noninvasive disease biomarker …

Cell-free DNA: an overview of sample types and isolation procedures

F Martignano - Cell-free DNA as Diagnostic Markers: Methods and …, 2019 - Springer
The study of cell-free DNA (cfDNA) is often challenging due to genomic DNA contamination,
low concentration, and high fragmentation. Therefore, it is important to optimize pre …

Guidelines for the preanalytical conditions for analyzing circulating cell-free DNA

R Meddeb, E Pisareva, AR Thierry - Clinical chemistry, 2019 - academic.oup.com
Circulating cell-free DNA (cfDNA) isolated from blood has been identified as a potential
biomarker in numerous fields, and has been the object of intensive research over the past …

New perspectives on the importance of cell-free DNA biology

AJ Bronkhorst, V Ungerer, A Oberhofer, S Gabriel… - Diagnostics, 2022 - mdpi.com
Body fluids are constantly replenished with a population of genetically diverse cell-free DNA
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …

Current and future perspectives of cell-free DNA in liquid biopsy

S Liu, J Wang - Current Issues in Molecular Biology, 2022 - mdpi.com
A liquid biopsy is a minimally invasive or non-invasive method to analyze a range of tumor
material in blood or other body fluids, including circulating tumor cells (CTCs), cell-free DNA …

Cell-free DNA: hope and potential application in cancer

Y Yan, Q Guo, F Wang, R Adhikari, Z Zhu… - Frontiers in cell and …, 2021 - frontiersin.org
Cell-free DNA (cfDNA) is easily accessible in peripheral blood and can be used as
biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA …

Toward the Development of a Circulating Free DNA-Based In Vitro Diagnostic Test for Infectious Diseases: a Review of Evidence for Tuberculosis

BL Fernández-Carballo, T Broger, R Wyss… - Journal of clinical …, 2019 - Am Soc Microbiol
The detection of circulating free DNA (cfDNA) has transformed the field of oncology and
prenatal diagnostics. Clinical application of cfDNA for disease diagnosis and monitoring …