The Brevinin peptides are antimicrobial agents obtained from frog skin secretions. Brevinin-
2R has attracted many attentions due to its very low hemolytic activity, cationic property, and …

Host-defense antimicrobial peptides (AMPs) from amphibians are usually considered as one
of the most promising next-generation antibiotics because of their excellent antimicrobial …

Cancer has always been one of the most common malignant diseases in the world.
Therefore, there is an urgent need to find potent agents with selective antitumor activity …

Abstract Brevinin-2R (BR-2R), a novel antimicrobial and anti-cancer peptide and two
derivatives, BR-C and BR-D, were well designed, synthesized and purified by RP-HPLC …

Amphibians are a natural source of abundant antimicrobial peptides and thus have been
widely investigated for isolation of such biomolecules. Many new antimicrobial peptide …

Antimicrobial peptide is one important component of the first protective barrier of organisms.
They not only have potent antimicrobial activity which can protect the body from the invading …

Introduction: Antimicrobial peptides as the body's defense strategy play an important role in
resistance against infection of microorganism. These peptides are able to modulate the …

Antimicrobial peptides (AMPs) are a class of molecules that play an essential role in innate
immune regulation. The Brevinin-1 family are AMPs that show strong pharmacological and …

Brevinin-1BYa (FLPILASLAAKFGPKLFCLVTKKC) is a cationic α-helical peptide containing
an intramolecular disulphide bridge that is present in skin secretions of the foothill yellow …

Brevinin-2R is an antimicrobial peptide which has been isolated from the skin of the frog
Rana ridibunda. The purpose of the present study was to examine the cellular cytotoxicity …