[HTML][HTML] Proposal for dosage adjustment and timing of chemotherapy in hemodialyzed patients

N Janus, J Thariat, H Boulanger, G Deray… - Annals of …, 2010 - Elsevier
Background The increased incidence of malignancies in patients with chronic renal failure
has been discussed since the mid-70s. On the other hand, the high frequency of chronic …

[HTML][HTML] Management of patients with end-stage renal disease undergoing chemotherapy: recommendations of the Associazione Italiana di Oncologia Medica (AIOM) …

P Pedrazzoli, N Silvestris, A Santoro, S Secondino… - Esmo Open, 2017 - Elsevier
Background The overall risk of some cancers is increased in patients receiving regular
dialysis treatment due to chronic oxidative stress, a weakened immune system and …

[HTML][HTML] Management of anticancer treatment in patients under chronic dialysis: results of the multicentric CANDY (CANcer and DialYsis) study

N Janus, V Launay-Vacher, A Thyss, H Boulanger… - Annals of oncology, 2013 - Elsevier
Background One million people worldwide benefit from chronic dialysis, with an increased
rate in Western countries of 5% yearly. Owing to increased incidence of cancer in dialyzed …

[HTML][HTML] Renal insufficiency and cancer treatments

V Launay-Vacher, N Janus, G Deray - ESMO open, 2016 - Elsevier
Renal insufficiency has been shown to be highly prevalent in patients with cancer. This renal
insufficiency has been reported to be associated with reduced overall survival and …

Dose recommendations for anticancer drugs in patients with renal or hepatic impairment

SD Krens, G Lassche, FGA Jansman… - The Lancet …, 2019 - thelancet.com
Renal or hepatic impairment is a common comorbidity for patients with cancer either
because of the disease itself, toxicity of previous anticancer treatments, or because of other …

[HTML][HTML] Renal insufficiency in elderly cancer patients: International Society of Geriatric Oncology clinical practice recommendations

V Launay-Vacher, E Chatelut, SM Lichtman… - Annals of oncology, 2007 - Elsevier
Background Elderly cancer patients commonly have renal function decline. This warrants
particular caution during the administration of renally excreted cancer drugs or those with …

Renal insufficiency and anticancer drugs in elderly cancer patients: a subgroup analysis of the IRMA study

V Launay-Vacher, JP Spano, N Janus… - Critical reviews in …, 2009 - Elsevier
The Renal Insufficiency and Anticancer Medications (IRMA) study is a French national,
observational study which demonstrated the high prevalence of abnormal renal function in a …

Cancer and renal insufficiency results of the BIRMA study

N Janus, V Launay-Vacher, E Byloos… - British journal of …, 2010 - nature.com
Background: Half of anticancer drugs are predominantly excreted in urine. Dosage
adjustment in renal insufficiency (RI) is, therefore, a crucial issue. Moreover, patients with …

Importance of monitoring renal function in patients with cancer

M Aapro, V Launay-Vacher - Cancer treatment reviews, 2012 - Elsevier
Monitoring renal function in patients with solid tumors and hematologic malignancies is vital
to the safe administration of therapeutic agents. Renal impairment is frequent in elderly …

Renal effects of targeted anticancer therapies

C Porta, L Cosmai, M Gallieni, P Pedrazzoli… - Nature Reviews …, 2015 - nature.com
The use of novel targeted anticancer agents has led to overall improvement in the prognosis
of many patients affected by various malignancies, but has also been associated with an …