MicroRNAs as potential regulators of immune response networks in asthma and chronic obstructive pulmonary disease

JA Cañas, JM Rodrigo-Muñoz, B Sastre… - Frontiers in …, 2021 - frontiersin.org
Chronic respiratory diseases (CRDs) are an important factor of morbidity and mortality,
accounting for approximately 6% of total deaths worldwide. The main CRDs are asthma and …

MicroRNA profiling in asthma: potential biomarkers and therapeutic targets

E Heffler, A Allegra, G Pioggia, G Picardi… - American journal of …, 2017 - atsjournals.org
Asthma is a heterogeneous chronic inflammatory disorder in which different endotypes
contribute to define clinical inflammatory phenotypes. MicroRNAs (miRNAs) are a group of …

MicroRNAs in chronic airway diseases: Clinical correlation and translational applications

BWQ Tan, WL Sim, JK Cheong, WS Kuan, T Tran… - Pharmacological …, 2020 - Elsevier
MicroRNAs (miRNAs) are short single-stranded RNAs that have pivotal roles in disease
pathophysiology through transcriptional and translational modulation of important genes. It …

Involvement of microRNAs in physiological and pathological processes in asthma

SR Mousavi, A Ahmadi, SA Jamalkandi… - Journal of cellular …, 2019 - Wiley Online Library
Asthma is the most common respiratory disease accompanied by lung inflammatory
disorders. The main symptoms are airway obstruction, chronic inflammation due to mast cell …

Molecular background of miRNA role in asthma and COPD: an updated insight

I Szymczak, J Wieczfinska… - BioMed research …, 2016 - Wiley Online Library
Inflammatory airway diseases are a significant health problems requiring new approaches to
the existing therapies and addressing fundamental issues. Difficulties in developing effective …

MicroRNAs in inflammatory lung disease-master regulators or target practice?

IK Oglesby, NG McElvaney, CM Greene - Respiratory research, 2010 - Springer
MicroRNAs (miRNAs) have emerged as a class of regulatory RNAs with immense
significance in numerous biological processes. When aberrantly expressed miRNAs have …

MicroRNAs: future biomarkers and targets of therapy in asthma?

K Specjalski, M Niedoszytko - Current opinion in pulmonary …, 2020 - journals.lww.com
Recent publications confirmed crucial regulatory role of miRNAs in the pathomechanism of
asthma. Some single miRNAs or their sets hold the promise for their use as asthma …

The emerging role of microRNAs in asthma

X Jiang - Molecular and cellular biochemistry, 2011 - Springer
Asthma is a common chronic airways disease that worldwide affects people from all ethnic
backgrounds. MicroRNAs (miRNAs) are small non-coding RNAs of 18–25 nucleotides that …

Role of microRNAs in inflammatory upper airway diseases

V Tubita, B Callejas‐Díaz, J Roca‐Ferrer, C Marin… - Allergy, 2021 - Wiley Online Library
MicroRNAs (miRNAs) are a conserved family of small endogenous noncoding RNA
molecules that modulate post‐transcriptional gene expression in physiological and …

Harnessing the power of miRNAs: the molecular architects of asthma pathogenesis and potential targets for therapeutic innovation

TM Al-Noshokaty, D Fathi, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Asthma is a chronic non-communicable respiratory disease that is characterized by airway
inflammation and hyperreactivity. Defective functions of airway smooth muscle and …