Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignancies

J Chen, M Foroozesh, Z Qin - Oncogenesis, 2019 - nature.com
Human endogenous retroviruses (HERVs), viral-associated sequences, are normal
components of the human genome and account for 8–9% of our genome. These original …

Human endogenous retrovirus reactivation: implications for cancer immunotherapy

A Petrizzo, C Ragone, B Cavalluzzo, A Mauriello… - Cancers, 2021 - mdpi.com
Simple Summary Endogenous viruses are “ancient” viruses that have coevolved with their
host species for millions of years, developing strategies to maintain an equilibrium state with …

Human endogenous retroviruses in cancer: Oncogenesis mechanisms and clinical implications

K Kitsou, P Lagiou, G Magiorkinis - Journal of Medical Virology, 2023 - Wiley Online Library
Abstract Human Endogenous Retroviruses (HERVs) are viral sequences integrated into the
human genome, resulting from the infection of human germ‐line cells by ancient exogenous …

Expressional activation and functional roles of human endogenous retroviruses in cancers

M Zhang, JQ Liang, S Zheng - Reviews in medical virology, 2019 - Wiley Online Library
Human endogenous retroviruses (HERVs) are widely believed to be remnants of ancestral
germ line infections by exogenous retroviruses. Although HERVs are deemed as …

HERVs and cancer—A comprehensive review of the relationship of human endogenous retroviruses and human cancers

E Stricker, EC Peckham-Gregory, ME Scheurer - Biomedicines, 2023 - mdpi.com
Genomic instability and genetic mutations can lead to exhibition of several cancer hallmarks
in affected cells such as sustained proliferative signaling, evasion of growth suppression …

Contribution of human retroviruses to disease development—a focus on the HIV–and HERV–cancer relationships and treatment strategies

CH Liu, N Grandi, L Palanivelu, E Tramontano, LT Lin - Viruses, 2020 - mdpi.com
Animal retroviruses are known for their transforming potential, and this is also true for the
ones hosted by humans, which have gathered expanding attention as one of the potent …

Human endogenous retroviruses (HERVs): shaping the innate immune response in cancers

V Alcazer, P Bonaventura, S Depil - Cancers, 2020 - mdpi.com
Human Endogenous Retroviruses (HERVs) are accounting for 8% of the human genome.
These sequences are remnants from ancient germline infections by exogenous retroviruses …

[HTML][HTML] Human endogenous retroviruses and their implication for immunotherapeutics of cancer

AS Attermann, AM Bjerregaard, SK Saini, K Grønbæk… - Annals of …, 2018 - Elsevier
Human endogenous retroviruses (HERVs) have recently caught increased attention as a
potential internal trigger to sensitize tumor cells to immunotherapies. HERVs are remnants of …

Activation of human endogenous retroviruses and its physiological consequences

N Dopkins, DF Nixon - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Human endogenous retroviruses (HERVs) are abundant sequences that persist within the
human genome as remnants of ancient retroviral infections. These sequences became fixed …

Human endogenous retroviruses in cancer: Expression, regulation and function

Y Gao, XF Yu, T Chen - Oncology Letters, 2021 - spandidos-publications.com
Human endogenous retroviruses (HERVs) are the remnants of ancient retroviruses that
infected human germline cells and became integrated into the human genome millions of …