Introduction Clinical studies have shown significant improvements in exercise capacity in
patients with chronic obstructive pulmonary disease (COPD) who are treated with a …

Background Reduced physical activity is associated with increased morbidity and mortality
in patients with COPD. Studies suggest that treatment with the long-acting muscarinic …

Background Maintaining and improving physical functioning is key to mitigating the cycle of
deconditioning associated with chronic obstructive pulmonary disease (COPD). We …

Objective We aim to determine the effect of a fixed-dose combination (FDC) of
tiotropium/olodaterol on Physical activity (PA) in patients with chronic obstructive pulmonary …

Background Patients with chronic obstructive pulmonary disease (COPD) show signs of
reduced physical activity from the early stages of the disease, impacting morbidity and …

Aim This observational study with tiotropium Respimat® was performed in a real-life setting
to investigate its effectiveness with regard to physical functioning and tolerability. Methods …

Background Both tiotropium (T) and olodaterol (O) monotherapies improve exercise
endurance in patients with chronic obstructive pulmonary disease (COPD). Objective To …

Background Comparative effects on physical activity of mono and dual bronchodilators
remain unclear in patients with treatment-naïve chronic obstructive pulmonary disease …

Two replicate, double-blind, 6-week, incomplete-crossover studies (MORACTO 1 and 2)
assessed the effects of tiotropium/olodaterol on inspiratory capacity and exercise endurance …

Purpose This study evaluated the efficacy of tiotropium/olodaterol vs tiotropium on lung
function, exercise capacity, and physical activity in patients with COPD. Patients and …