Neural tube closure takes place during early embryogenesis and requires interactions
between genetic and environmental factors. Failure of neural tube closure is a common …

This review provides a brief description of folate use and folic acid metabolism in relation to
neural tube defect (NTD) risk. First, a meta‐analysis of reduction in NTD recurrence and …

Neural tube defects (NTDs), including anencephaly and spina bifida, arise from the failure of
neurulation during early embryonic development. Neural tube defects are common birth …

Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …

Neural tube defects (NTDs) are common complex congenital malformations resulting from
failure of the neural tube closure during embryogenesis. It is established that folic acid …

Neural tube defects (NTDs) refer to a cluster of neurodevelopmental conditions associated
with failure of neural tube closure during embryonic development. Worldwide prevalence of …

Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …

Neural tube defects (NTDs), a common birth defect in humans, result from the failure of the
embryonic neural tube (NT) to close properly. NT closure is a complex, poorly understood …

Neural tube defects (NTD) remain a major cause of morbidity in spite of the reduction in
liveborn incidence with periconceptional folic acid. However, the etiology remains unknown …

Neural tube and orofacial defects are common congenital malformations in humans. While
etiologically heterogeneous, they are for the most part multifactorial in their pathogenesis …