Dual pathway inhibition with rivaroxaban and aspirin reduces inflammatory biomarkers in atherosclerosis

V Russo, D Fabiani, S Leonardi, E Attena… - Journal of …, 2023 - journals.lww.com
Dual pathway inhibition (DPI) with low-dose rivaroxaban and aspirin in patients with
coronary artery disease (CAD) and/or peripheral artery disease (PAD) reduces the …

Synergistic influence of rivaroxaban on inflammation and coagulation biomarkers in patients with coronary artery disease and peripheral artery disease on aspirin …

U Tantry, C Cummings, P Mackrell, M Gonze… - Future …, 2020 - Taylor & Francis
COMPASS study demonstrated efficacy of dual pathway inhibition with 2.5 mg twice daily
rivaroxaban and aspirin in patients with polyvascular disease (coronary artery disease …

Pharmacodynamic profiles of dual-pathway inhibition with or without clopidogrel versus dual antiplatelet therapy in patients with atherosclerotic disease

M Galli, F Franchi, F Rollini, L Been… - Thrombosis and …, 2022 - thieme-connect.com
Aim Inhibition of thrombin-mediated signaling processes using a vascular dose of
rivaroxaban in adjunct to antiplatelet therapy, known as dual-pathway inhibition (DPI) …

Dual pathway inhibition for atherosclerotic cardiovascular disease: Recent advances

S Carlin, TAC de Vries, A Budaj… - … Polska (Polish Heart …, 2022 - journals.viamedica.pl
Atherosclerotic cardiovascular disease (ASCVD), which includes coronary artery disease
(CAD), cerebrovascular disease, and peripheral arterial disease (PAD) is associated with …

Low-dose rivaroxaban: can cardiovascular events be reduced?

L De Luca - European Heart Journal Supplements, 2023 - academic.oup.com
Despite available effective guideline-based preventive therapies, patients with vascular
diseases remain at high-risk of recurrent ischaemic events. Novel therapeutic strategies are …

Dual pathway inhibition as compared to acetylsalicylic acid monotherapy in relation to endothelial function in peripheral artery disease, a phase IV clinical trial

LH Willems, DHJ Thijssen, LA Groh… - Frontiers in …, 2022 - frontiersin.org
Objective Dual pathway inhibition (DPI) by combining acetylsalicylic acid (ASA) with low-
dose rivaroxaban has been shown to reduce cardiovascular events in patients with …

Patients selected for dual pathway inhibition in clinical practice have similar characteristics and outcomes to those included in the COMPASS randomized trial: The …

KAA Fox, V Aboyans, ES Debus… - European Heart …, 2022 - academic.oup.com
Aims To determine the characteristics of patients with coronary artery disease (CAD),
peripheral artery disease (PAD), or both, initiating dual pathway inhibition (DPI) using …

Net clinical benefit of extended dual pathway inhibition according to baseline risk in patients with chronic coronary syndrome: a COMPASS substudy

M Würtz, KKW Olesen, DL Bhatt, S Yusuf… - European Heart …, 2024 - academic.oup.com
Aims Guidelines recommend extended dual pathway inhibition (DPI) with aspirin and
rivaroxaban in patients with chronic coronary syndrome (CCS) at high ischaemic risk. The …

Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications

M Galli, F Franchi, F Rollini, L Ortega-Paz… - Expert review of …, 2023 - Taylor & Francis
Introduction The persistence of elevated rates of ischemic recurrences despite the use of
antiplatelet therapy among patients with atherosclerotic disease together with the …

Dual pathway inhibition for vascular protection in patients with atherosclerotic disease: rationale and review of the evidence

JI Weitz, DJ Angiolillo, T Geisler… - Thrombosis and …, 2020 - thieme-connect.com
Despite advances in secondary prevention strategies in patients with cardiovascular
disease, the residual risk of recurrent atherothrombotic events remains high. Dual …