Cell-penetrating peptides: design, synthesis, and applications
DM Copolovici, K Langel, E Eriste, U Langel - ACS nano, 2014 - ACS Publications
The intrinsic property of cell-penetrating peptides (CPPs) to deliver therapeutic molecules
(nucleic acids, drugs, imaging agents) to cells and tissues in a nontoxic manner has …
(nucleic acids, drugs, imaging agents) to cells and tissues in a nontoxic manner has …
Cell-penetrating peptides as delivery vehicles for biology and medicine
KM Stewart, KL Horton, SO Kelley - Organic & biomolecular chemistry, 2008 - pubs.rsc.org
Cell-penetrating peptides (CPPs) have found numerous applications in biology and
medicine since the first synthetic cell-permeable sequence was identified two decades ago …
medicine since the first synthetic cell-permeable sequence was identified two decades ago …
Cell penetrating peptides: efficient vectors for delivery of nanoparticles, nanocarriers, therapeutic and diagnostic molecules
SM Farkhani, A Valizadeh, H Karami, S Mohammadi… - Peptides, 2014 - Elsevier
Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable …
challenge. The cellular membrane is very effective in its role as a selectively permeable …
Recent advances in selective and targeted drug/gene delivery systems using cell-penetrating peptides
SH Nam, J Park, H Koo - Archives of Pharmacal Research, 2023 - Springer
Biological cell membranes are a natural barrier for living cells. In the last few decades, the
cell membrane has been the main hurdle in the efficient delivery of bioactive and therapeutic …
cell membrane has been the main hurdle in the efficient delivery of bioactive and therapeutic …
Cell-penetrating peptides: strategies for anticancer treatment
D Raucher, JS Ryu - Trends in molecular medicine, 2015 - cell.com
Cell-penetrating peptides (CPP) provide an efficient strategy for the intracellular delivery of
bioactive molecules in various biomedical applications. This review focuses on recent …
bioactive molecules in various biomedical applications. This review focuses on recent …
Mechanism matters: a taxonomy of cell penetrating peptides
The permeability barrier imposed by cellular membranes limits the access of exogenous
compounds to the interior of cells. Researchers and patients alike would benefit from …
compounds to the interior of cells. Researchers and patients alike would benefit from …
Applications and challenges for use of cell-penetrating peptides as delivery vectors for peptide and protein cargos
The hydrophilic nature of peptides and proteins renders them impermeable to cell
membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics …
membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics …
Intracellular delivery of molecular cargo using cell-penetrating peptides and the combination strategies
H Li, TY Tsui, W Ma - International journal of molecular sciences, 2015 - mdpi.com
Cell-penetrating peptides (CPPs) can cross cellular membranes in a non-toxic fashion,
improving the intracellular delivery of various molecular cargos such as nanoparticles, small …
improving the intracellular delivery of various molecular cargos such as nanoparticles, small …
Cell penetration: scope and limitations by the application of cell‐penetrating peptides
S Reissmann - Journal of Peptide Science, 2014 - Wiley Online Library
The penetration of polar or badly soluble compounds through a cell membrane into live cells
requires mechanical support or chemical helpers. Cell‐penetrating peptides (CPPs) are very …
requires mechanical support or chemical helpers. Cell‐penetrating peptides (CPPs) are very …
Recent advances in cell penetrating peptide-based anticancer therapies
J Habault, JL Poyet - Molecules, 2019 - mdpi.com
Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …