The function of the respiratory chain is closely associated with kidney function, and the
dysfunction of the respiratory chain is a primary pathophysiological change in chronic kidney …

In healthy kidneys, interstitial fibroblasts are responsible for the maintenance of renal
architecture. Progressive interstitial fibrosis is thought to be a common pathway for chronic …

Chronic kidney disease (CKD) is associated with a variety of distinct disease processes that
permanently change the function and structure of the kidney across months or years. CKD is …

Mitochondria are important organelles in eukaryotic cells and perform a variety of
biosynthetic and metabolic functions. Many human diseases are closely related to …

The kidney contains many mitochondria that generate ATP to provide energy for cellular
processes. Oxidative stress injury can be caused by impaired mitochondria with excessive …

Cardiovascular disease (CVD) frequently complicates chronic kidney disease (CKD). The
risk of all-cause mortality increases from 20% to 500% in patients who suffer both conditions; …

Mitochondria are heterogeneous and highly dynamic organelles, playing critical roles in
adenosine triphosphate (ATP) synthesis, metabolic modulation, reactive oxygen species …

Background: Renal diseases remain an increasing public health issue affecting millions of
people. The kidney is a highly energetic organ that is rich in mitochondria. Numerous …

The kidney contains many mitochondria that generate ATP to provide energy for cellular
processes. Oxidative stress injury can be caused by impaired mitochondria with excessive …

Mitochondria are ubiquitous intracellular organelles found in almost all eukaryotes and
involved in various aspects of cellular life, with a primary role in energy production. The …