The addition of an amine group to a heteroaromatic system is a challenging synthetic
process, yet it is an essential one in the development of many bioactive molecules. Here, we …

A practicable quinoline synthesis from aniline and two amino acids was developed for
generating a wide range of quinolines with high efficiency and diversity. Thus, it facilitated …

Herein, a catalytic synthetic transformation offering a series of-NH2 group-bearing
aminoisoquinolines with moderate to good yields has been showcased. Interestingly, the …

Hydrazonamides are fundamental building blocks in many pharmaceuticals and agricultural
chemicals. Although previous transformations have been accomplished through multi-step …

Naphthalene monoimide (NMI) molecules have recently been discovered to act as a
powerful reductant to trigger strong C–Cl bond cleavage reactions. In this report, we explore …

Herein, a rapid alkenylation of quinoxalin-2 (1H)-ones enabled by a combination of Mannich-
type reaction and solar photocatalysis is demonstrated. A wide range of functional groups …

Polysubstituted quinolin-3-amines are vital structural motifs because of their broad biological
activities as well as versatile transformational abilities. However, they are not easily …

Reduction of nitroarenes constitutes an important route to high value-added products. It is
highly desirable but remains a challenge that this process occurs with selectivity under mild …

Herein, a novel aqueous reaction for the olefination of quinoxalin-2 (1H)-ones with ketones
through a combinational strategy is described. This reaction features very mild conditions …

Quinolin-2 (1H)-ones are one of the important classes of compounds due to their prevalence
in natural products and in pharmacologically useful compounds. Here we present an …