Skeletal rearrangement through photocatalytic denitrogenation: access to C-3 aminoquinolin-2 (1 H)-ones
The addition of an amine group to a heteroaromatic system is a challenging synthetic
process, yet it is an essential one in the development of many bioactive molecules. Here, we …
process, yet it is an essential one in the development of many bioactive molecules. Here, we …
Divergent synthesis of functionalized quinolines from aniline and two distinct amino acids
JC Xiang, ZX Wang, Y Cheng, SQ Xia… - The Journal of …, 2017 - ACS Publications
A practicable quinoline synthesis from aniline and two amino acids was developed for
generating a wide range of quinolines with high efficiency and diversity. Thus, it facilitated …
generating a wide range of quinolines with high efficiency and diversity. Thus, it facilitated …
Nitrogen Atom Transfer Enables the (5+ 1) Annulation Reaction to Access Aminoisoquinolines
Herein, a catalytic synthetic transformation offering a series of-NH2 group-bearing
aminoisoquinolines with moderate to good yields has been showcased. Interestingly, the …
aminoisoquinolines with moderate to good yields has been showcased. Interestingly, the …
Photocatalyzed intermolecular amination for the synthesis of hydrazonamides
W Guo, L Cai, Z Xie, W Mei, G Liu, L Deng… - Organic Chemistry …, 2021 - pubs.rsc.org
Hydrazonamides are fundamental building blocks in many pharmaceuticals and agricultural
chemicals. Although previous transformations have been accomplished through multi-step …
chemicals. Although previous transformations have been accomplished through multi-step …
Unlocking the photo-dehydrogenation ability of naphthalene monoimide towards the synthesis of quinazolinones
Naphthalene monoimide (NMI) molecules have recently been discovered to act as a
powerful reductant to trigger strong C–Cl bond cleavage reactions. In this report, we explore …
powerful reductant to trigger strong C–Cl bond cleavage reactions. In this report, we explore …
Rapid alkenylation of quinoxalin-2 (1H)-ones enabled by the sequential Mannich-type reaction and solar photocatalysis
L Huang, J Xu, L He, C Liang, Y Ouyang, Y Yu… - Chinese Chemical …, 2021 - Elsevier
Herein, a rapid alkenylation of quinoxalin-2 (1H)-ones enabled by a combination of Mannich-
type reaction and solar photocatalysis is demonstrated. A wide range of functional groups …
type reaction and solar photocatalysis is demonstrated. A wide range of functional groups …
Modular synthesis of polysubstituted quinolin-3-amines by oxidative cyclization of 2-(2-isocyanophenyl) acetonitriles with organoboron reagents
S Wang, J Xu, Q Song - Organic Letters, 2021 - ACS Publications
Polysubstituted quinolin-3-amines are vital structural motifs because of their broad biological
activities as well as versatile transformational abilities. However, they are not easily …
activities as well as versatile transformational abilities. However, they are not easily …
Photo-induced redox cascade reaction of nitroarenes and amines
XZ Shao, GY Xu, W Fan, S Zhang, MB Li - Organic Chemistry Frontiers, 2023 - pubs.rsc.org
Reduction of nitroarenes constitutes an important route to high value-added products. It is
highly desirable but remains a challenge that this process occurs with selectivity under mild …
highly desirable but remains a challenge that this process occurs with selectivity under mild …
A combination of heterogeneous catalysis and photocatalysis for the olefination of quinoxalin-2 (1 H)-ones with ketones in water: a green and efficient route to (Z) …
J Xu, L Huang, L He, Z Ni, J Shen, X Li, K Chen… - Green …, 2021 - pubs.rsc.org
Herein, a novel aqueous reaction for the olefination of quinoxalin-2 (1H)-ones with ketones
through a combinational strategy is described. This reaction features very mild conditions …
through a combinational strategy is described. This reaction features very mild conditions …
Efficient visible light mediated synthesis of quinolin-2 (1 H)-ones from quinoline N-oxides
Quinolin-2 (1H)-ones are one of the important classes of compounds due to their prevalence
in natural products and in pharmacologically useful compounds. Here we present an …
in natural products and in pharmacologically useful compounds. Here we present an …