Variation matters: TLR structure and species-specific pathogen recognition
Toll-like receptors (TLRs) are a family of pattern recognition receptors that are an important
link between innate and adaptive immunity. Many vaccines incorporate ligands for TLRs as …
link between innate and adaptive immunity. Many vaccines incorporate ligands for TLRs as …
Engagement of TLR signaling as adjuvant: towards smarter vaccine and beyond
A Lahiri, P Das, D Chakravortty - Vaccine, 2008 - Elsevier
Toll like receptors (TLRs) are a family of conserved pattern recognition receptors that
recognizes specific microbial patterns and allow the cell to distinguish between self and non …
recognizes specific microbial patterns and allow the cell to distinguish between self and non …
[HTML][HTML] A comparative review of toll-like receptor 4 expression and functionality in different animal species
C Vaure, Y Liu - Frontiers in immunology, 2014 - frontiersin.org
Toll-like receptors (TLRs) belong to the pattern recognition receptor (PRR) family, a key
component of the innate immune system. TLRs detect invading pathogens and initiate an …
component of the innate immune system. TLRs detect invading pathogens and initiate an …
Of mice and men: species variations of Toll-like receptor expression
M Rehli - Trends in immunology, 2002 - cell.com
Toll-like receptors (TLRs) comprise a family of evolutionary conserved pattern recognition
molecules that have an essential role in mammalian innate immune defense. Recent …
molecules that have an essential role in mammalian innate immune defense. Recent …
Mammalian Toll-like receptors: to immunity and beyond
PA Hopkins, S Sriskandan - Clinical & Experimental …, 2005 - academic.oup.com
Toll-like receptors (TLRs) constitute an archetypal pattern recognition system. Their
sophisticated biology underpins the ability of innate immunity to discriminate between highly …
sophisticated biology underpins the ability of innate immunity to discriminate between highly …
[HTML][HTML] Exploiting viral sensing mediated by Toll-like receptors to design innovative vaccines
Toll-like receptors (TLRs) are transmembrane proteins belonging to the family of pattern-
recognition receptors. They function as sensors of invading pathogens through recognition …
recognition receptors. They function as sensors of invading pathogens through recognition …
[HTML][HTML] Contrasted evolutionary histories of two Toll-like receptors (Tlr4 and Tlr7) in wild rodents (MURINAE)
Background In vertebrates, it has been repeatedly demonstrated that genes encoding
proteins involved in pathogen-recognition by adaptive immunity (eg MHC) are subject to …
proteins involved in pathogen-recognition by adaptive immunity (eg MHC) are subject to …
Translational mini-review series on Toll-like receptors: recent advances in understanding the role of Toll-like receptors in anti-viral immunity
AG Bowie - Clinical & Experimental Immunology, 2007 - academic.oup.com
Toll-like receptors (TLRs) respond to pathogens to initiate the innate immune response and
direct adaptive immunity, and evidence to date suggests that they have a role in the …
direct adaptive immunity, and evidence to date suggests that they have a role in the …
Toll-like receptors: linking innate and adaptive immunity
C Pasare, R Medzhitov - … of lymphocyte activation and immune regulation …, 2005 - Springer
Work in recent years has shown an essential role for Toll-like receptors (TLRs) in the
activation of innate and adaptive immunity in vertebrate animals. These germ-line encoded …
activation of innate and adaptive immunity in vertebrate animals. These germ-line encoded …
[HTML][HTML] Signatures of positive selection in Toll-like receptor (TLR) genes in mammals
H Areal, J Abrantes, PJ Esteves - BMC evolutionary biology, 2011 - Springer
Abstract Background Toll-like receptors (TLRs) are a major class of pattern recognition
receptors (PRRs) expressed in the cell surface or membrane compartments of immune and …
receptors (PRRs) expressed in the cell surface or membrane compartments of immune and …