[HTML][HTML] Inflammatory response to spinal cord injury and its treatment

X Liu, Y Zhang, Y Wang, T Qian - World neurosurgery, 2021 - Elsevier
Spinal cord injury (SCI), as one of the intractable diseases in clinical medicine, affects
thousands of human beings, and the pathologic changes after injury have been a hot spot …

[HTML][HTML] The pathophysiological role of acute inflammation after spinal cord injury

S Okada - Inflammation and regeneration, 2016 - Springer
Traumatic spinal cord injury (SCI) causes irreparable severe motor and sensory dysfunction.
Mechanical trauma rapidly leads to blood-spinal cord barrier disruption, neural cell death …

[HTML][HTML] Inflammation: a target for treatment in spinal cord injury

X Freyermuth-Trujillo, JJ Segura-Uribe… - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) is a significant cause of disability, and treatment alternatives that
generate beneficial outcomes and have no side effects are urgently needed. SCI may be …

Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications

S David, R López-Vales, VW Yong - Handbook of clinical neurology, 2012 - Elsevier
Spinal cord injury (SCI) results in immediate damage followed by a secondary phase of
tissue damage that occurs over a period of several weeks. The mechanisms underlying this …

[HTML][HTML] Current therapeutic strategies for inflammation following traumatic spinal cord injury☆

PL Singh, N Agarwal, JC Barrese… - Neural regeneration …, 2012 - journals.lww.com
Damage from spinal cord injury occurs in two phases–the trauma of the initial mechanical
insult and a secondary injury to nervous tissue spared by the primary insult. Apart from …

Modulating the immune response in spinal cord injury

A Ulndreaj, JCT Chio, CS Ahuja… - Expert review of …, 2016 - Taylor & Francis
In spinal cord injury (SCI), the primary mechanical trauma is followed by a secondary injury
cascade which expands the susceptible perilesional region and produces further permanent …

Insights into the dual role of inflammation after spinal cord injury

R Rust, J Kaiser - Journal of Neuroscience, 2017 - Soc Neuroscience
Injuries to the CNS lead to severe and often irreversible deficits in sensorimotor and
autonomous function. In spinal cord injury (SCI), mechanical damage results in the death of …

Acute spinal cord injury: A review of pathophysiology and potential of non-steroidal anti-inflammatory drugs for pharmacological intervention

E Hayta, H Elden - Journal of Chemical Neuroanatomy, 2018 - Elsevier
Acute spinal cord injury (SCI) is one of the serious central nervous system injuries, which
can lead to significant neurological impairments and a reduction in quality of life with loss in …

Regulation of inflammatory cytokines for spinal cord injury recovery

S Lin, C Xu, J Lin, H Hu, C Zhang, X Mei - 2021 - digitum.um.es
Spinal cord injury (SCI) is one of the most destructive traumatic diseases in human beings.
The balance of inflammation in the microenvironment is crucial to the repair process of …

[HTML][HTML] Inflammation & apoptosis in spinal cord injury

N Zhang, Y Yin, SJ Xu, YP Wu… - Indian journal of medical …, 2012 - journals.lww.com
Spinal cord injury (SCI) consists of a two-steps process involving a primary mechanical
injury followed by an inflammatory process and apoptosis. Secondary insult is characterized …