Objective: Although heritability explains a large proportion of the variance in old-age
cognition, studies on the influence of specific genes have been inconclusive. We …

Associations between genotypes and cognitive outcomes may provide clues as to which
mechanisms cause individual differences in old-age cognitive performance. We investigated …

We examined the association of 28 single nucleotide polymorphisms (SNPs), previously
associated with dementia or cognitive performance, with tests assessing episodic memory …

Genetic polymorphisms of apolipoprotein E (APOE) and brain-derived neurotrophic factor
(BDNF) have shown inconsistent associations with healthy adult cognitive functions. Recent …

Age-related changes in memory are not uniform, even in the absence of dementia.
Characterization of non-disease associated cognitive changes is crucial to gain a more …

Most people's cognitive abilities decline with age, with significant and partly genetically
driven, individual differences in rate of change. Although APOE ɛ4 and genetic scores for …

The brain-derived neurotrophic factor (BDNF) plays an important role in activity-dependent
synaptic plasticity, which underlies learning and memory. In a sample of 948 younger and …

Introduction. A family history of Alzheimer's disease is a significant risk factor for its onset, but
the genetic risk associated with possessing multiple risk alleles is still poorly understood …

Cognitive decline is a feared aspect of growing old. It is a major contributor to lower quality
of life and loss of independence in old age. We investigated the genetic contribution to …

The study aim was to estimate the genetic contribution to individual differences in different
forms of memory in a large family-based group of older adults. As part of the Late Onset …