[HTML][HTML] Magnesium sulfate prevents placental ischemia-induced increases in brain water content and cerebrospinal fluid cytokines in pregnant rats

LW Zhang, JP Warrington - Frontiers in Neuroscience, 2016 - frontiersin.org
Magnesium sulfate (MgSO4) is the most widely used therapy in the clinic to prevent the
progression of preeclampsia, a hypertensive disorder of pregnancy, to eclampsia …

Magnesium sulfate provides neuroprotection in eclampsia-like seizure model by ameliorating neuroinflammation and brain edema

X Li, X Han, J Yang, J Bao, X Di, G Zhang, H Liu - Molecular neurobiology, 2017 - Springer
Eclampsia is a hypertensive disorder of pregnancy that is defined by the new onset of grand
mal seizures on the basis of preeclampsia and a leading cause of maternal and fetal …

Magnesium sulfate (MG) prevents maternal inflammation induced offspring cerebral injury evident on MRI but not via IL-1β

Y Ginsberg, N Khatib, B Weiss, S Arison, MG Ross… - Neuroscience, 2017 - Elsevier
Objective: As maternal treatment with magnesium sulfate (MG) may protect the fetal brain,
we sought to assess the inflammation associated neuroprotective potential of MG and its …

Magnesium sulphate neuroprotection mechanism is placental mediated by inhibition of inflammation, apoptosis and oxidative stress

N Khatib, Y Ginsberg, CB David, MG Ross, D Vitner… - Placenta, 2022 - Elsevier
Introduction Maternal inflammation may induce placental cytokine production resulting in
fetal exposure, and development of neonatal neurologic injury. Maternal magnesium …

[HTML][HTML] Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia

AC Johnson, SM Tremble, SL Chan, J Moseley… - PloS one, 2014 - journals.plos.org
Eclampsia, defined as unexplained seizure in a woman with preeclampsia, is a life-
threatening complication of pregnancy with unclear etiology. Magnesium sulfate (MgSO4) is …

Magnesium sulfate reduces inflammation-associated brain injury in fetal mice

I Burd, K Breen, A Friedman, J Chai… - American journal of …, 2010 - Elsevier
OBJECTIVE: The purpose of this study was to investigate whether magnesium sulfate
(MgSO4) prevents fetal brain injury in inflammation-associated preterm birth (PTB). STUDY …

Neuroprotective effect of long-term MgSO4 administration after cerebral hypoxia-ischemia in newborn rats is related to the severity of brain damage

E Spandou, V Soubasi… - Reproductive …, 2007 - journals.sagepub.com
Previous studies have shown contradictory results regarding magnesium-mediated
neuroprotection in animal models of perinatal asphyxia. The aim of this study is to …

The protective effect of magnesium sulfate on placental inflammation via suppressing the NF-κB pathway in a preeclampsia-like rat model

Y Wu, F Kang, Y Yang, L Tao, Y Chen, X Li - Pregnancy Hypertension, 2023 - Elsevier
Abnormal placental inflammation has a role in the pathophysiology of preeclampsia.
Magnesium sulfate (MgSO 4) has anti-inflammatory properties and is a fetal neuroprotective …

Fetal neuroprotective mechanism of maternal magnesium sulfate for late gestation inflammation: in a rodent model

N Khatib, Y Ginsberg, E Shalom-Paz… - The Journal of …, 2020 - Taylor & Francis
Background: Maternal administration of magnesium sulfate (Mg) is used in humans to
protect the fetal brain during preterm delivery. We sought to determine the neuroprotective …

Neuroprotective effects of antenatal magnesium sulfate under inflammatory conditions in a Sprague–Dawley pregnant rat model

A Binette, S Blouin, A Ardilouze… - The Journal of Maternal …, 2017 - Taylor & Francis
Abstract Objective: Antenatal magnesium sulfate (MgSO4) is recommended for fetal
neuroprotection. The aim of this animal study was to assess the neuroprotective effect of in …