Candidiasis and Mechanisms of Antifungal Resistance

S Bhattacharya, S Sae-Tia, BC Fries - Antibiotics, 2020 - mdpi.com
Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which
is caused by more than 20 types of Candida sp., with C. albicans being the most common …

Antifungal drug resistance among Candida species: mechanisms and clinical impact

M Sanguinetti, B Posteraro, C Lass‐Flörl - Mycoses, 2015 - Wiley Online Library
The epidemiology of Candida infections has changed in recent years. Although Candida
albicans is still the main cause of invasive candidiasis in most clinical settings, a substantial …

Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Candida albicans—The Virulence Factors and Clinical Manifestations of Infection

J Talapko, M Juzbašić, T Matijević, E Pustijanac… - Journal of Fungi, 2021 - mdpi.com
Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity,
gastrointestinal and vaginal tract, and healthy individuals' skin. In 50% of the population, C …

Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species

SG Whaley, EL Berkow, JM Rybak… - Frontiers in …, 2017 - frontiersin.org
Within the limited antifungal armamentarium, the azole antifungals are the most frequent
class used to treat Candida infections. Azole antifungals such as fluconazole are often …

Antifungal drug resistance mechanisms

J Pemán, E Cantón, A Espinel-Ingroff - Expert review of anti …, 2009 - Taylor & Francis
Antifungal resistance is a prominent feature in the management of invasive mycoses, with
important implications for morbidity and mortality. Microbiological resistance, the most …

[图书][B] Candida and candidiasis

RA Calderone, CJ Clancy - 2011 - books.google.com
The underlying mechanisms of Candida and candidiasis and promising new directions in
drug discovery and treatment.• Reviews all aspects of this common fungal pathogen and its …

[HTML][HTML] Resistance of Candida to azoles and echinocandins worldwide

KE Pristov, MA Ghannoum - Clinical Microbiology and Infection, 2019 - Elsevier
Background Recently there has been an increase in Candida infections worldwide. A
handful of species in the genus Candida are opportunistic pathogens and have been known …

[HTML][HTML] Antifungal drug-resistance mechanisms in Candida biofilms

J Kaur, CJ Nobile - Current opinion in microbiology, 2023 - Elsevier
Highlights•Few classes of antifungal drugs currently exist to treat fungal infections.•Infections
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …

The effect of antifungal resistance development on the virulence of Candida species

F Bohner, C Papp, A Gácser - FEMS Yeast Research, 2022 - academic.oup.com
In recent years, the relevance of diseases associated with fungal pathogens increased
worldwide. Members of the Candida genus are responsible for the greatest number of fungal …