Pharmacological therapies and factors delivery for spinal cord injury regeneration
Spinal cord injury (SCI) is one of the major causes of irreversible nerve injury, affecting both
sensory and motor neurons, which poses a significant physical, emotional, and economic …
sensory and motor neurons, which poses a significant physical, emotional, and economic …
A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury
N Hejrati, MG Fehlings - Current Opinion in Pharmacology, 2021 - Elsevier
Traumatic spinal cord injuries (SCIs) have far-reaching physical, social, and financial
consequences. While medical advancements have improved supportive therapeutic …
consequences. While medical advancements have improved supportive therapeutic …
Drug delivery, cell-based therapies, and tissue engineering approaches for spinal cord injury
S Kabu, Y Gao, BK Kwon, V Labhasetwar - Journal of Controlled Release, 2015 - Elsevier
Spinal cord injury (SCI) results in devastating neurological and pathological consequences,
causing major dysfunction to the motor, sensory, and autonomic systems. The primary …
causing major dysfunction to the motor, sensory, and autonomic systems. The primary …
Clinical and experimental advances in regeneration of spinal cord injury
Spinal cord injury (SCI) is one of the major disabilities dealt with in clinical rehabilitation
settings and is multifactorial in that the patients suffer from motor and sensory impairments …
settings and is multifactorial in that the patients suffer from motor and sensory impairments …
Recent advances in regenerative medicine approaches for spinal cord injuries
Traumatic injury to the spinal cord leads to a loss of motor and sensory function below the
level of injury. The lack of growth-associated proteins, local expression of inhibitory factors …
level of injury. The lack of growth-associated proteins, local expression of inhibitory factors …
[HTML][HTML] Sustained delivery of neurotrophic factors to treat spinal cord injury
A Muheremu, L Shu, J Liang, A Aili… - Translational …, 2021 - degruyter.com
Acute spinal cord injury (SCI) is a devastating condition that results in tremendous physical
and psychological harm and a series of socioeconomic problems. Although neurons in the …
and psychological harm and a series of socioeconomic problems. Although neurons in the …
Translational perspective: neuroregenerative strategies and therapeutics for traumatic spinal cord injury
AJ Santamaria, PM Saraiva, JP Solano… - Neural Repair and …, 2022 - Elsevier
The last three decades have witnessed transformative advances in biology and
neuroscience. Still, regeneration of axons after traumatic spinal cord injury (SCI) remains a …
neuroscience. Still, regeneration of axons after traumatic spinal cord injury (SCI) remains a …
Spinal cord injury: plasticity, regeneration and the challenge of translational drug development
A Blesch, MH Tuszynski - Trends in neurosciences, 2009 - cell.com
Over the past three decades, multiple mechanisms limiting central nervous system
regeneration have been identified. Here, we address plasticity arising from spared systems …
regeneration have been identified. Here, we address plasticity arising from spared systems …
Spinal cord clinical trials and the role for bioengineering
JT Wilcox, D Cadotte, MG Fehlings - Neuroscience letters, 2012 - Elsevier
There is considerable need for bringing effective therapies for spinal cord injury (SCI) to the
clinic. Excellent medical and surgical management has mitigated poor prognoses after SCI; …
clinic. Excellent medical and surgical management has mitigated poor prognoses after SCI; …
Neuroprotection and regeneration strategies for spinal cord repair
EC Tsai, CH Tator - Current pharmaceutical design, 2005 - ingentaconnect.com
The journey toward a cure for spinal cord injury (SCI) has taken many paths. In this article,
we review these paths, and highlight the clinical applications of these experimental repair …
we review these paths, and highlight the clinical applications of these experimental repair …
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