Neurons are highly polarised, complex and incredibly energy intensive cells, and their
demand for ATP during neuronal transmission is primarily met by oxidative phosphorylation …

Highlights•Neuronal mitochondria show compartment-specific morphology in dendrites and
axons.•Genetically-encoded tools allow for monitoring of many mitochondrial functions in …

Mitochondria have a number of essential roles in neuronal function. Their complex mobility
patterns within neurons are characterized by frequent changes in direction. Mobile …

Cells precisely regulate mitochondrial movement in order to balance energy needs and
avoid cell death. Neurons are particularly susceptible to disturbance of mitochondrial motility …

Mitochondria fulfill numerous cellular functions including ATP production, Ca2+ buffering,
neurotransmitter synthesis and degradation, ROS production and sequestration, apoptosis …

The complex and elaborate architecture of a neuron poses a great challenge to the cellular
machinery which localizes proteins and organelles, such as mitochondria, to necessary …

Neuronal postsynaptic currents consume most of the brain's energy supply. Delineating how
neurons control the distribution, morphology and function of the energy‐producing …

Mitochondria are essential organelles for neuronal growth, survival, and function. Neurons
use specialized mechanisms to drive mitochondria transport and to anchor them in axons …

Mitochondria are cellular power plants that supply ATP to power various biological activities
essential for neuronal growth, survival, and function. Due to unique morphological features …

Recent findings have sparked renewed appreciation for the remarkably dynamic nature of
mitochondria. These organelles constantly fuse and divide, and are actively transported to …