Ten adults with the nephrotic syndrome and sterile pyuria are described. On biopsy they had
varying degrees of glomerular sclerosis without proliferation. Interstitial inflammation and …

Introduction The value of renal biopsy in the diagnosis and management of the nephrotic
syndrome appears well established. 1-5 We have observed eight adults with severe …

THE nephrotic syndrome, a clinical entity characterized by edema, proteinuria,
hypoalbuminemia and hypercholesterolemia, may occur in the adult during the course of …

Excerpt The nephrotic syndrome is a disorder of diverse causes which occurs as a primary
or secondary form of renal disease and exhibits variable pathologic features (1-8). Its …

SUMMARY A survey of renal biopsies of Si patients with the nephrotic syndrome not due to
lupus erythematosus, renal amyloidosis, diabetic glomerulosclerosis or one of the …

We describe 49 patients who developed a nephrotic syndrome after the age of 15 years, and
who showed a 'minimal change'pattern in their renal biopsies. Patients with sclerosing …

Focal glomerular sclerosis was diagnosed in nine patients by renal biopsy. Proteinuria,
hematuria, hypertension, and slowly progressive renal insufficiency unresponsive to …

This long-term study analyzes the prognostic value of the quantitative urinary protein
excretion during and following steroid administration, the renal functional status three years …

Advances in our understanding of the mechanisms of proteinuria in humans have depended
on a variety of animal models. Most of these have been partially satisfactory because they …

In a series of patients with the nephrotic syndrome, we have undertaken an evaluation of
renal biopsy with respect to (1) variability in interpretation among observers, and (2) …