Purpose Since chromosomal abnormalities can be detected in more than half of
miscarriages, cytogenetic testing of the product of conception (POC) can provide important …

Purpose Chromosomal abnormalities are a major cause of spontaneous abortion, and
conventional G‐banded karyotyping (G‐banding) is mainly utilized for chromosomal …

Objective Cytogenetic analysis of POC using tissue culture has limitations including long
time to results, culture failure, and MCC. The objective of this study is to report our initial …

Background Fetal chromosomal abnormalities was the most frequent cause of miscarriage,
and the traditional testing method G-banded karyotyping has limitations. Then high …

Background Cytogenetic evaluation of products of conception (POC) for chromosomal
abnormalities is central to determining the cause of pregnancy loss. We compared the test …

Background Cytogenetic analysis of products of conception (POC) is essential for the
management of recurrent pregnancy loss (RPL), but the currently-performed G-banding …

Approximately 30% of pregnancies after implantation end up in spontaneous abortions, and
50% of them are caused by chromosomal abnormalities. However, the spectrum of genomic …

Background Traditional testing of miscarriage products involved culture of tissue followed by
G-banded chromosome analysis; this approach has a high failure rate, is labour intensive …

Massively parallel genome sequencing, also known as next-generation sequencing (NGS),
is the latest approach for preimplantation genetic diagnosis. The purpose of this study was to …

Purpose To analyze the molecular cytogenetic data obtained from products of conception
(POC) obtained by selective biopsy of first trimester miscarriages and to estimate the rate of …