Corynebacterium pseudotuberculosis is a prominent human and animal pathogen causing
chronic inflammatory diseases. Interleukin-1β (IL-1β) is involved in the response to such …

Mycobacterium bovis is the causative agent of tuberculosis in a wide range of mammals,
including humans. Macrophages are the first line of host defense. They secrete …

As a hallmark of tuberculosis (TB), Mycobacterium tuberculosis (MTB) induces
granulomatous lung lesions and systemic inflammatory responses during active disease …

Mycobacterium kansasii has emerged as an important nontuberculous mycobacterium
pathogen, whose incidence and prevalence have been increasing in the last decade. M …

Summary Interleukin‐1β (IL‐1β) represents one of the most important mediators of
inflammation and host responses to infection. Mycobacterium tuberculosis (Mtb), the …

Objective Tuberculosis infection of the Central Nervous System can cause severe
inflammation in microglia, and NLRP3 inflammasome is also an important source of …

The development of effective innate and subsequent adaptive host immune responses is
highly dependent on the production of proinflammatory cytokines that increase the activity of …

Pathogenic mycobacteria, such as Mycobacterium tuberculosis, Mycobacterium bovis, and
Mycobacterium marinum, can trigger NLRP3 inflammasome activation leading to maturation …

Lysosomal cathepsin B (CTSB) has been proposed to play a role in the induction of acute
inflammation. We hypothesised that the presence of active CTSB in the cytosol is crucial for …

Inflammation is an extensively concerted process that confers protection to the host
encountering immune insult. The major inflammatory mediators include IL-1 family …