The effects of cannabidiol and prognostic role of TRPV2 in human endometrial cancer

O Marinelli, MB Morelli, D Annibali, C Aguzzi… - International journal of …, 2020 - mdpi.com
Several studies support, both in vitro and in vivo, the anti-cancer effects of cannabidiol
(CBD), a transient receptor potential vanilloid 2 (TRPV2) ligand. TRPV2, often dysregulated …

Cannabinoid-induced cell death in endometrial cancer cells: involvement of TRPV1 receptors in apoptosis

BM Fonseca, G Correia-da-Silva… - Journal of physiology and …, 2018 - Springer
Among a variety of phytocannabinoids, Δ 9-tetrahydrocannabinol (THC) and cannabidiol
(CBD) are the most promising therapeutic compounds. Besides the well-known palliative …

Can cannabidiol inhibit angiogenesis in colon cancer?

M Honarmand, F Namazi, A Mohammadi… - Comparative Clinical …, 2019 - Springer
Colon cancer is the third most common human malignancy and a main cause of death
worldwide. The current study was carried out to investigate the effects of cannabidiol, a …

∆ 9‑tetrahydrocannabinol inhibits epithelial‑mesenchymal transition and metastasis by targeting matrix metalloproteinase‑9 in endometrial cancer

Y Zhang, W Zheng, K Shen, W Shen - Oncology letters, 2018 - spandidos-publications.com
Limited therapeutic interventions are clinically available for treating aggressive endometrial
cancer (EC). Therefore, effective therapies are urgently required. Therefore, the present …

Anti-proliferative effect of Cannabidiol in Prostate cancer cell PC3 is mediated by apoptotic cell death, NFκB activation, increased oxidative stress, and lower reduced …

J Li, T Gu, S Hu, B Jin - Plos one, 2023 - journals.plos.org
Prostate cancer is the second most frequent cancer diagnosed in men in the world today.
Almost all prostate cancers are adenocarcinomas and develop from gland cells. We used …

Cannabidiol inhibits tumorigenesis in cisplatin-resistant non-small cell lung cancer via TRPV2

S Misri, K Kaul, S Mishra, M Charan, AK Verma… - Cancers, 2022 - mdpi.com
Simple Summary Drug resistance is the key factor contributing to the therapeutic failure of
lung cancer and the deaths related to lung cancer. Our study demonstrated that small …

Synergistic interactions of cannabidiol with chemotherapeutic drugs in mcf7 cells: Mode of interaction and proteomics analysis of mechanisms

MA Alsherbiny, DJ Bhuyan, MN Low, D Chang… - International journal of …, 2021 - mdpi.com
Cannabidiol (CBD), a nonpsychoactive phytocannabinoid, has recently emerged as a
potential cytotoxic agent in addition to its ameliorative activity in chemotherapy-associated …

Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by reversing epithelial–mesenchymal transition through the Wnt/β-catenin signaling pathway

PF Feng, LX Zhu, J Jie, PX Yang, N Sheng… - Journal of Cancer …, 2023 - Springer
Colorectal cancer (CRC) is the leading cause of cancer deaths worldwide, wherein distant
metastasis is the main reason for death. The non-psychoactive phytocannabinoid …

Cannabidiol induces cell cycle arrest and cell apoptosis in human gastric cancer SGC-7901 cells

X Zhang, Y Qin, Z Pan, M Li, X Liu, X Chen, G Qu… - Biomolecules, 2019 - mdpi.com
The main chemical component of cannabis, cannabidiol (CBD), has been shown to have
antitumor properties. The present study examined the in vitro effects of CBD on human …

[HTML][HTML] Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: Novel anti-tumor mechanisms of Cannabidiol in breast cancer

M Elbaz, MW Nasser, J Ravi, NA Wani, DK Ahirwar… - Molecular …, 2015 - Elsevier
The anti-tumor role and mechanisms of Cannabidiol (CBD), a non-psychotropic cannabinoid
compound, are not well studied especially in triple-negative breast cancer (TNBC). In the …