Current Strategy of Monoclonal Antibody: Development, Cloning, Formulation and Drug Delivery

R Kaliyaperumal, S Ranganathan… - Recent Advances in …, 2023 - ingentaconnect.com
The development of Monoclonal antibodies (mAbs) has also allowed researchers to
understand the complexity of diseases better and find new treatments for difficult-to-treat …

Therapeutic antibodies—Delivering the promise?

G Hale - Advanced drug delivery reviews, 2006 - Elsevier
For more than a century, therapeutic antibodies held the promise of providing specific cures
for a wide range of diseases. It was not till the monoclonal era that the difficulties with purity …

Monoclonal Antibodies as Biopharmaceuticals

GJ Kotwal - … Drug Delivery Systems: Concepts, Technology, and …, 2012 - Wiley Online Library
In the 36 years since the methodology of generating monoclonal antibodies (mAbs) was
introduced, mAbs have become the most therapeutically useful and economically lucrative …

Therapeutic use of monoclonal antibodies: general aspects and challenges for drug delivery

DA Quinteros, JM Bermúdez, S Ravetti, A Cid… - Nanostructures for drug …, 2017 - Elsevier
Monoclonal antibodies are routinely used in several fields but the great challenge has been
their use as therapeutic agents for the treatment of diseases, such as breast cancer …

Historical development of monoclonal antibody therapeutics

A Nissim, Y Chernajovsky - Therapeutic antibodies, 2008 - Springer
Since the first publication by Kohler and Milstein on the production of mouse monoclonal
antibodies (mAbs) by hybridoma technology, mAbs have had a profound impact on …

Monoclonal antibodies: recent development in drug delivery

S Ashique, PM Guptha, J Kanoujia, A Garg… - … and Nano Drug Delivery, 2024 - Elsevier
Awareness to monoclonal antibodies (mABs) has been intensely increasing yearly. Due to
highly specific targeting of antigens, mABs can be used for the treatment of various type of …

Clinical application of monoclonal antibodies in targeted therapy

M Superson, K Szmyt, K Szymańska, K Walczak… - 2019 - repozytorium.ur.edu.pl
Introduction. Recently, monoclonal antibodies (mAbs) have become powerful human
therapeutics in the diagnosis and treatment of many diseases. Drugs based on mAbs are …

[HTML][HTML] Monoclonal antibodies: from benchtop to bedside

JPF Bai - Therapeutic Delivery, 2011 - Taylor & Francis
Therapeutic Delivery (2011) 2 (3) 330 future science group 402 publications. Replacing
'Phase II'with 'Phase I'yielded 372 publications. Since clinical trials are time consuming, this …

Monoclonal antibodies: formulations of marketed products and recent advances in novel delivery system

Y Cui, P Cui, B Chen, S Li, H Guan - Drug development and …, 2017 - Taylor & Francis
Monoclonal antibodies (mAbs) are extensively employed for disease diagnosis and
treatment because of their high homogeneity and antigen specificity. In recent years …

Challenges in monoclonal antibody-based therapies

H Samaranayake, T Wirth, D Schenkwein… - Annals of …, 2009 - Taylor & Francis
Therapeutic monoclonal antibodies (mAbs) are the fastest growing class of new therapeutic
molecules. They hold great promises for the treatment of a variety of diseases, including …