[HTML][HTML] ENO2 promotes anoikis resistance in anaplastic thyroid cancer by maintaining redox homeostasis
Y Zhang, X Ji, Y Wang - Gland Surgery, 2024 - ncbi.nlm.nih.gov
Background Anoikis presents a significant barrier in the metastasis of cancer. As the most
aggressive type of thyroid cancer, anaplastic thyroid cancer (ATC) exhibits a high risk of …
aggressive type of thyroid cancer, anaplastic thyroid cancer (ATC) exhibits a high risk of …
[HTML][HTML] α-Enolase lies downstream of mTOR/HIF1α and promotes thyroid carcinoma progression by regulating CST1
Y Liu, L Liao, C An, X Wang, Z Li, Z Xu… - Frontiers in Cell and …, 2021 - frontiersin.org
Novel therapy strategies are crucial for thyroid carcinoma treatment. It is increasingly
important to clarify the mechanism of thyroid carcinoma progression. Several studies …
important to clarify the mechanism of thyroid carcinoma progression. Several studies …
Tumor susceptibility gene 101 mediates anoikis resistance of metastatic thyroid cancer cells
K Saharat, K Lirdprapamongkol… - Cancer Genomics & …, 2018 - cgp.iiarjournals.org
Background/Aim: Resistance to anoikis is a pre-requisite step in metastasis, a major cause
of death in patients with cancer, including thyroid cancer. Impairing anoikis resistance is a …
of death in patients with cancer, including thyroid cancer. Impairing anoikis resistance is a …
[HTML][HTML] Anoctamin5 regulates cell migration and invasion in thyroid cancer
Z Chang, C Cai, D Han, Y Gao… - International …, 2017 - newslettern.spandidos-publications …
Anoctamin/TMEM16 family members have recently been identified as novel calcium-
activated chloride channels, and dysregulation of many family members participates in …
activated chloride channels, and dysregulation of many family members participates in …
[HTML][HTML] Lysyl oxidase promotes anaplastic thyroid carcinoma cell proliferation and metastasis mediated via BMP1
Y Liu, Y Zhang, Z Tan, J Wang, Y Hu, J Sun, M Bao… - Gland …, 2022 - ncbi.nlm.nih.gov
Background Anaplastic thyroid carcinoma (ATC) is an extremely aggressive solid tumor with
no effective treatment at present. Because of the rapid growth and aggressiveness, nearly all …
no effective treatment at present. Because of the rapid growth and aggressiveness, nearly all …
FOXK2 transcriptionally activating VEGFA induces apatinib resistance in anaplastic thyroid cancer through VEGFA/VEGFR1 pathway
H Feng, Z Jin, J Liang, Q Zhao, L Zhan, Z Yang, J Yan… - Oncogene, 2021 - nature.com
Anaplastic thyroid carcinoma (ATC) is a rare and extremely aggressive type of thyroid
cancer, and the potential mechanisms involved in ATC progression remains unclarified. In …
cancer, and the potential mechanisms involved in ATC progression remains unclarified. In …
The deubiquitinating enzyme ATXN3 promotes the progression of anaplastic thyroid carcinoma by stabilizing EIF5A2
S Zhuang, J Xie, J Zhen, L Guo, Z Hong, F Li… - Molecular and Cellular …, 2021 - Elsevier
Abstract Ataxin-3 (ATXN3) is a ubiquitous deubiquitinating enzyme that plays an essential
role in the carcinogenesis of numerous tumors and stabilizes the expression of substrates by …
role in the carcinogenesis of numerous tumors and stabilizes the expression of substrates by …
[HTML][HTML] OVOL2 impairs RHO GTPase signaling to restrain mitosis and aggressiveness of Anaplastic Thyroid Cancer
M Gugnoni, G Manzotti, E Vitale, E Sauta… - Journal of Experimental …, 2022 - Springer
Abstract Background Anaplastic Thyroid Cancer (ATC) is an undifferentiated and aggressive
tumor that often originates from well-Differentiated Thyroid Carcinoma (DTC) through a trans …
tumor that often originates from well-Differentiated Thyroid Carcinoma (DTC) through a trans …
[HTML][HTML] Targeting NOX4 disrupts the resistance of papillary thyroid carcinoma to chemotherapeutic drugs and lenvatinib
P Tang, J Sheng, X Peng, R Zhang, T Xu, J Hu… - Cell Death …, 2022 - nature.com
Advanced differentiated thyroid cancer cells are subjected to extreme nutritional starvation
which contributes to develop resistance to treatments; however, the underlying mechanism …
which contributes to develop resistance to treatments; however, the underlying mechanism …
Targeting tumor hypoxia inhibits aggressive phenotype of dedifferentiated thyroid cancer
B Ma, S Wen, Y Luo, T Zhang, Y Yang… - The Journal of …, 2023 - academic.oup.com
Context Hypoxia is commonly observed in multiple aggressive cancers. Its role remains
unclear in the biology and therapy of dedifferentiated thyroid cancer (DDTC). Objective We …
unclear in the biology and therapy of dedifferentiated thyroid cancer (DDTC). Objective We …