Background Anoikis presents a significant barrier in the metastasis of cancer. As the most
aggressive type of thyroid cancer, anaplastic thyroid cancer (ATC) exhibits a high risk of …

Novel therapy strategies are crucial for thyroid carcinoma treatment. It is increasingly
important to clarify the mechanism of thyroid carcinoma progression. Several studies …

Background/Aim: Resistance to anoikis is a pre-requisite step in metastasis, a major cause
of death in patients with cancer, including thyroid cancer. Impairing anoikis resistance is a …

Anoctamin/TMEM16 family members have recently been identified as novel calcium-
activated chloride channels, and dysregulation of many family members participates in …

Background Anaplastic thyroid carcinoma (ATC) is an extremely aggressive solid tumor with
no effective treatment at present. Because of the rapid growth and aggressiveness, nearly all …

Anaplastic thyroid carcinoma (ATC) is a rare and extremely aggressive type of thyroid
cancer, and the potential mechanisms involved in ATC progression remains unclarified. In …

Abstract Ataxin-3 (ATXN3) is a ubiquitous deubiquitinating enzyme that plays an essential
role in the carcinogenesis of numerous tumors and stabilizes the expression of substrates by …

Abstract Background Anaplastic Thyroid Cancer (ATC) is an undifferentiated and aggressive
tumor that often originates from well-Differentiated Thyroid Carcinoma (DTC) through a trans …

Advanced differentiated thyroid cancer cells are subjected to extreme nutritional starvation
which contributes to develop resistance to treatments; however, the underlying mechanism …

Context Hypoxia is commonly observed in multiple aggressive cancers. Its role remains
unclear in the biology and therapy of dedifferentiated thyroid cancer (DDTC). Objective We …