Mouse oocytes injected with testicular spermatozoa or round spermatids can develop into normal offspring
Y Kimura, R Yanagimachi - Development, 1995 - journals.biologists.com
Genomic imprinting occurs in both male and female gametes during gametogenesis, but the
exact time when imprinting begins and ends is unknown. In the present study we injected …
exact time when imprinting begins and ends is unknown. In the present study we injected …
Birth of normal young after electrofusion of mouse oocytes with round spermatids.
A Ogura, J Matsuda… - Proceedings of the …, 1994 - National Acad Sciences
Normally, round spermatids, the youngest male germ cells with a set of haploid
chromosomes, cannot fertilize mature oocytes. However, when mouse spermatids were …
chromosomes, cannot fertilize mature oocytes. However, when mouse spermatids were …
Development of normal mice from oocytes injected with secondary spermatocyte nuclei
Y Kimura, R Yanagimachi - Biology of reproduction, 1995 - academic.oup.com
This study shows that the nucleus of the secondary spermatocyte can participate in syngamy
and normal embryonic development. Spermatogenic cells were released from the …
and normal embryonic development. Spermatogenic cells were released from the …
Status of genomic imprinting in mouse spermatids
FL Shamanski, Y Kimura, MC Lavoir… - Human …, 1999 - academic.oup.com
The advent of human round spermatid microinjection (ROSI) into oocytes as a treatment for
severe male infertility raises the question of whether spermatids have undergone all of the …
severe male infertility raises the question of whether spermatids have undergone all of the …
Development of normal mice from metaphase I oocytes fertilized with primary spermatocytes
A Ogura, O Suzuki, K Tanemura… - Proceedings of the …, 1998 - National Acad Sciences
Primary spermatocytes are the male germ cells before meiosis I. To examine whether these
4n diploid cells are genetically competent to fertilize oocytes and support full embryo …
4n diploid cells are genetically competent to fertilize oocytes and support full embryo …
Full term development of mouse eggs fertilized by a spermatozoon microinjected under the zona pellucida
JR Mann - Biology of Reproduction, 1988 - academic.oup.com
A mature motile mouse spermatozoon was microinjected under the zona pellucida of mouse
eggs. Twenty-five percent of eggs were fertilized, and 54% of these developed to normal …
eggs. Twenty-five percent of eggs were fertilized, and 54% of these developed to normal …
Alternative sources of gametes: reality or science fiction?
MC Tsai, T Takeuchi, JM Bedford, MM Reis… - Human …, 2000 - academic.oup.com
Although great progress has been made in both the investigation and treatment of infertility,
a considerable number of patients still fail to conceive. Spermatogenic failure and/or oocyte …
a considerable number of patients still fail to conceive. Spermatogenic failure and/or oocyte …
Developmental potential of mouse primordial germ cells
Y Kato, WM Rideout, K Hilton, SC Barton… - …, 1999 - journals.biologists.com
There are distinctive and characteristic genomic modifications in primordial germ cells that
distinguish the germ cell lineage from somatic cells. These modifications include, genome …
distinguish the germ cell lineage from somatic cells. These modifications include, genome …
[引用][C] Fertilization of an oocyte microinseminated with a spermatid in an in-vitro fertilization programme
P Vanderzwalmen, B Lejeune, M Nij… - Human …, 1995 - academic.oup.com
We wish to report the successful fertilization of a human oocyte by a late-stage spermatid by
the use of intracytoplasmic sperm injection (ICSI). Our previous work has shown that …
the use of intracytoplasmic sperm injection (ICSI). Our previous work has shown that …
Intracytoplasmic sperm injection experiments using the mouse as a model
R Yanagimachi - Human Reproduction, 1998 - academic.oup.com
Due to the existence of ample background information on its reproduction, embryology and
genetics, the mouse is potentially an excellent animal model for intracytoplasmic sperm …
genetics, the mouse is potentially an excellent animal model for intracytoplasmic sperm …