Fibrosis, a common process of chronic inflammatory diseases, is defined as a repair
response disorder when organs undergo continuous damage, ultimately leading to scar …

Fibrosis, a process caused by excessive deposition of extracellular matrix (ECM), is a
common cause and outcome of organ failure and even death. Researchers have made …

DNA methylation is a major epigenetic mechanism to regulate gene expression. Epigenetic
regulation, including DNA methylation, histone modifications and RNA interference, results …

Fibrosis is a progressive and potentially fatal process that can occur in numerous organ
systems. Characterised by the excessive deposition of extracellular matrix proteins such as …

Myocardial fibrosis (MF) is a reactive remodeling process in response to myocardial injury. It
is mainly manifested by the proliferation of cardiac muscle fibroblasts and secreting …

Fibrosis is a common and important disease. It is a pathological state due to excessive scar
formation mediated by an increase in activated fibroblasts that express alpha smooth muscle …

Fibrotic disease, which is implicated in almost half of all deaths worldwide, is the result of an
uncontrolled wound healing response to injury in which tissue is replaced by deposition of …

Diseases of the heart and the kidney, including heart failure and chronic kidney disease, can
dramatically impair life expectancy and the quality of life of patients. The heart and kidney …

Novel insights into the epigenetic control of chronic liver diseases are now emerging.
Recent advances in our understanding of the critical roles of DNA methylation, histone …

Abstract Background N6‐methyladenosine (m6A) is of great importance in renal physiology
and disease progression, but its function and mechanism in renal fibrosis remain to be …