Effect of intensive therapy on the development and progression of diabetic nephropathy in
the Diabetes Control and Complications Trial. The Diabetes Control and Complications Trial …

Background Intensive diabetes treatment reduces the risk of developing albuminuria in
individuals with type 1 diabetes. Effects on the long-term clinical course of kidney disease …

Background Long-term microvascular and neurologic complications cause major morbidity
and mortality in patients with insulin-dependent diabetes mellitus (IDDM). We examined …

Baseline analysis of renal function in the Diabetes Control and Complications Trial. To
determine whether there are relationships between nephropathy, retinopathy and putative …

Background Aggressive glycemic control has been hypothesized to prevent renal disease in
patients with type 2 diabetes mellitus. A systematic review was conducted to summarize the …

Sustained Effect of Intensive Treatment of Type 1 Diabetes Mellitus on Development and
Progression of Diabetic Nephropathy - PMC Back to Top Skip to main content NIH NLM Logo …

OBJECTIVE This multicenter study examined the impact of albumin excretion rate (AER) on
the course of estimated glomerular filtration rate (eGFR) and the incidence of sustained …

The effect of intensive glucose control on major kidney outcomes in type 2 diabetes remains
unclear. To study this, the ADVANCE trial randomly assigned 11,140 participants to an …

Background Among patients with type 1 diabetes mellitus, intensive therapy (with the aim of
achieving near-normal blood glucose and glycosylated hemoglobin concentrations) …

To evaluate the effect of multifactorial intervention on the onset and progression of diabetic
kidney disease in the patients with type 2 diabetes, we analyzed the effects of intensified …