Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent …
YF Kuo, YZ Su, YH Tseng, SY Wang, HM Wang… - Free Radical Biology …, 2010 - Elsevier
Flavonoids synthesized from chalcone precursors in plants have been shown to possess
cytotoxic activities with therapeutic potential. We have isolated the novel chalcone …
cytotoxic activities with therapeutic potential. We have isolated the novel chalcone …
Anticancer activities of chalcone flavokawain B from Alpinia pricei Hayata in human lung adenocarcinoma (A549) cells via induction of reactive oxygen species …
YC Hseu, YC Huang, V Thiyagarajan… - Journal of Cellular …, 2019 - Wiley Online Library
Chalcones found in fruits and vegetables have promising cancer chemopreventive
properties. This study attempts to identify the anticancer efficacies of chalcone flavokawain B …
properties. This study attempts to identify the anticancer efficacies of chalcone flavokawain B …
The Chalcone Flavokawain B Induces G2/M Cell-Cycle Arrest and Apoptosis in Human Oral Carcinoma HSC-3 Cells through the Intracellular ROS Generation and …
Chalcones have been described to represent cancer chemopreventive food components
that are rich in fruits and vegetables. In this study, we examined the anti-oral cancer effect of …
that are rich in fruits and vegetables. In this study, we examined the anti-oral cancer effect of …
Baicalein induces caspase‐dependent apoptosis associated with the generation of ROS and the activation of AMPK in human lung carcinoma A549 cells
HJ Kim, C Park, MH Han, SH Hong… - Drug Development …, 2016 - Wiley Online Library
ABSTRACT Preclinical Research Baicalein is one of the main bioactive flavonoids found in
the roots of Scutellaria baicalensis Georgi. Here, we report that baicalein‐induced growth …
the roots of Scutellaria baicalensis Georgi. Here, we report that baicalein‐induced growth …
Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo
Flavokawain B is a natural chalcone isolated from the rhizomes of Alpenia pricei Hayata. In
the present study, we have investigated the antiproliferative and apoptotic effect of …
the present study, we have investigated the antiproliferative and apoptotic effect of …
Galangin induces apoptosis in hepatocellular carcinoma cells through the caspase 8/t-Bid mitochondrial pathway
HT Zhang, J Wu, M Wen, LJ Su… - Journal of Asian natural …, 2012 - Taylor & Francis
This study has investigated whether galangin, a flavonol derived from Alpinia officinarum
Hance and used as food additives in southern China, induces apoptosis in hepatocellular …
Hance and used as food additives in southern China, induces apoptosis in hepatocellular …
Growth inhibitory effect of paratocarpin E, a prenylated chalcone isolated from Euphorbia humifusa Wild., by induction of autophagy and apoptosis in human breast …
S Gao, D Sun, G Wang, J Zhang, Y Jiang, G Li… - Bioorganic …, 2016 - Elsevier
Five flavones, including four flavonoids and one prenylated chalcone (paratocarpin E), were
isolated from E. humifusa. and their chemical structures were established by spectroscopic …
isolated from E. humifusa. and their chemical structures were established by spectroscopic …
Dulxanthone A induces cell cycle arrest and apoptosis via up‐regulation of p53 through mitochondrial pathway in HepG2 cells
Z Tian, J Shen, AP Moseman, Q Yang… - … journal of cancer, 2008 - Wiley Online Library
Natural products derived from plants provide a rich source for development of new
anticancer drugs. Dulxanthone A was found to be an active cytotoxic component in Garcinia …
anticancer drugs. Dulxanthone A was found to be an active cytotoxic component in Garcinia …
Chalcone flavokawain B induces autophagic-cell death via reactive oxygen species-mediated signaling pathways in human gastric carcinoma and suppresses tumor …
CT Chang, YC Hseu, V Thiyagarajan, KY Lin… - Archives of …, 2017 - Springer
Flavokawain B (FKB), a naturally occurring chalcone in kava extracts, has been reported to
possess anticancer activity. However, the effect of FKB on gastric cancer remains unclear …
possess anticancer activity. However, the effect of FKB on gastric cancer remains unclear …
[HTML][HTML] Induction of apoptosis and cell cycle arrest by flavokawain C on HT-29 human colon adenocarcinoma via enhancement of reactive oxygen species generation …
CW Phang, SA Karsani… - Pharmacognosy …, 2017 - ncbi.nlm.nih.gov
Chalcones have been shown to exhibit anti-cancer properties by targeting multiple
molecular pathways. It was, therefore, of interest to investigate flavokawain C (FKC), a …
molecular pathways. It was, therefore, of interest to investigate flavokawain C (FKC), a …
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