Omicron variants of SARS-CoV-2 have spread rapidly worldwide; however, most infected
patients have mild or no symptoms. This study aimed to understand the host response to …

The mechanisms driving SARS-CoV-2 susceptibility remain poorly understood, especially
the factors determining why unvaccinated individuals remain uninfected despite high-risk …

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to
nearly every continent, registering over 1,250,000 deaths worldwide. The effects of SARS …

Severe manifestations of coronavirus disease 2019 (COVID-19) and mortality have been
associated with physiological alterations that provide insights into the pathogenesis of the …

COVID-19 is a systemic infection that exerts significant impact on the metabolism. Yet, there
is little information on how SARS-CoV-2 affects metabolism. Using NMR spectroscopy, we …

Viral sepsis has been proposed as an accurate term to describe all multisystemic
dysregulations and clinical findings in severe and critically ill COVID-19 patients. The …

Background Deep metabolomic, proteomic and immunologic phenotyping of patients
suffering from an infection with severe acute respiratory syndrome coronavirus 2 (SARS …

Viruses hijack host metabolic pathways for their replicative advantage. In this study, using
patient-derived multiomics data and in vitro infection assays, we aimed to understand the …

The metabolic characteristics of COVID-19 disease are still largely unknown. Here, 44
patients with COVID-19 (31 mild COVID-19 patients and 13 severe COVID-19 patients), 42 …

SARS-CoV-2 and its mutant strains continue to rapidly spread with high infection and fatality.
Large-scale SARS-CoV-2 vaccination provides an important guarantee for effective …