Loperamide is an over‐the‐counter peripheral mu‐opioid agonist commonly used to
manage diarrhoea. When taken in an excessive dose, loperamide's penetration of the …

Current data suggest that the opioid epidemic represents a worsening problem in the United
States. However, prescribing rates of opioids have been steadily declining, suggesting that …

This case report describes a patient with opioid use disorder who developed cardiac toxicity
secondary to non-medical use of loperamide. At recommended doses, loperamide remains …

Loperamide is a μ-opioid receptor agonist with antidiarrhoeal effects. It is considered to have
a low abuse potential because of substantial first-pass metabolism and P-glycoprotein …

Loperamide is an over-the-counter medication which is commonly used to treat diarrhoea. In
excessive doses, loperamide acts as an opioid on the central nervous system, which …

Loperamide is a common over-the-counter antidiarrheal considered safe in a broad range of
dosages and thought devoid of abuse potential. We describe the first case of a patient with …

Loperamide is widely available as an inexpensive, over-the-counter remedy commonly used
for management of diarrhea. Although an opioid, at therapeutic doses it acts primarily on the …

Background Loperamide is a mu-opioid receptor agonist that is available as an over-the-
counter anti-motility agent in the US and UK; recommended maximum doses of 12-16 …

Loperamide is an antidiarrheal agent available as an inexpensive over-the-counter (OTC)
medication. In general, it is considered to be safe, but lately, loperamide drug abuse has …

Discussion In the United States, loperamide is approved by the US Food and Drug
Administration (FDA) in doses up to 16 mg daily for the treatment of acute and chronic …