Background: The endogenous cannabinoid system participates in the regulation of energy
balance, and its dysregulation may be implicated in the pathogenesis of obesity. Adipose …

Endoannabinoids regulate energy balance by modulating hypothalamic circuits controlling
food intake and energy expenditure. However, convincing evidence has accumulated …

Context: Cannabinoid CB1 receptor blockade decreases weight and hyperinsulinemia in
obese animals and humans in a way greatly independent from food intake. Objective: The …

We recently showed that the peripheral cannabinoid receptor type 1 (CNR1) gene is
upregulated by the synthetic glucocorticoid dexamethasone. CNR1 is highly expressed in …

The endocannabinoid system (ECS) has emerged as one of the most relevant regulators of
energy balance. The ECS acts through two cannabinoid receptors: types 1 and 2 (CB1 and …

Mounting evidence suggests that the endocannabinoid system regulates energy metabolism
through direct effects on peripheral tissues as well as central effects that regulate appetite …

The endocannabinoid system has recently emerged as an important modulator of several
functions of adipose tissue, including cell proliferation, differentiation and secretion. Here …

Context: The cannabinoid receptor 1 gene (CNR1) is implicated in adipocyte function.
Objective: We investigated human adipose tissue CNR1 mRNA in relation to obesity, clinical …

The endocannabinoid system is involved in a wide range of processes including the control
of energy acquisition and expenditure. Endocannabinoids and their receptors are present in …

The endocannabinoid system has been suspected to contribute to the association of visceral
fat accumulation with metabolic diseases. We determined whether circulating …