[HTML][HTML] Autophagy-related signaling pathways are involved in cancer
C Chen, H Gao, X Su - Experimental and Therapeutic …, 2021 - spandidos-publications.com
Autophagy is a self-digestion process in cells that can maintain energy homeostasis under
normal circumstances. However, misfolded proteins, damaged mitochondria and other …
normal circumstances. However, misfolded proteins, damaged mitochondria and other …
[HTML][HTML] Molecular mechanisms of autophagy in cancer development, progression, and therapy
VAM Vitto, S Bianchin, AA Zolondick, G Pellielo… - Biomedicines, 2022 - mdpi.com
Autophagy is an evolutionarily conserved and tightly regulated process that plays an
important role in maintaining cellular homeostasis. It involves regulation of various genes …
important role in maintaining cellular homeostasis. It involves regulation of various genes …
[HTML][HTML] The dual role of autophagy in cancer development and a therapeutic strategy for cancer by targeting autophagy
CW Yun, J Jeon, G Go, JH Lee, SH Lee - International journal of …, 2020 - mdpi.com
Autophagy is a delicate intracellular degradation process that occurs due to diverse stressful
conditions, including the accumulation of damaged proteins and organelles as well as …
conditions, including the accumulation of damaged proteins and organelles as well as …
[HTML][HTML] Understanding the role of autophagy in cancer formation and progression is a real opportunity to treat and cure human cancers
Simple Summary The modulation of autophagy represents a potential therapeutic strategy
for cancer. More than one hundred clinical trials have been conducted or are ongoing to …
for cancer. More than one hundred clinical trials have been conducted or are ongoing to …
[HTML][HTML] Autophagy regulation in cancer development and therapy
Autophagy is a cellular process to degrade long-lived or malfunctioning proteins and
obsolete or damaged organelles. It maintains cellular homeostasis and helps cells survive …
obsolete or damaged organelles. It maintains cellular homeostasis and helps cells survive …
[HTML][HTML] Dual roles of autophagy and their potential drugs for improving cancer therapeutics
DW Shin - Biomolecules & Therapeutics, 2020 - ncbi.nlm.nih.gov
Autophagy is a major catabolic process that maintains cell metabolism by degrading
damaged organelles and other dysfunctional proteins via the lysosome. Abnormal …
damaged organelles and other dysfunctional proteins via the lysosome. Abnormal …
Autophagy as a therapeutic target in cancer
N Chen, V Karantza - Cancer biology & therapy, 2011 - Taylor & Francis
Autophagy is a self-catabolic process that maintains intracellular homeostasis and prolongs
cell survival under stress via lysosomal degradation of cytoplasmic constituents and …
cell survival under stress via lysosomal degradation of cytoplasmic constituents and …
Autophagy as a molecular target for cancer treatment
Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
[HTML][HTML] Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect
SM Lim, EA Mohamad Hanif, SF Chin - Cell & bioscience, 2021 - Springer
Autophagy is a conserved cellular process required to maintain homeostasis. The hallmark
of autophagy is the formation of a phagophore that engulfs cytosolic materials for …
of autophagy is the formation of a phagophore that engulfs cytosolic materials for …
[HTML][HTML] The roles of autophagy in cancer
CW Yun, SH Lee - International journal of molecular sciences, 2018 - mdpi.com
Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …