Objective and Design: To investigate the role of nitric oxide (NO) in the liver injury induced
by delayed-type hypersensitivity to picryl chloride (PCl-DTH).¶ Materials and Methods: Liver …

The degree of acute hepatic failure after severe trauma and sepsis is related to the extent of
hepatocyte (HC) damage and cell death resulting from either necrosis or apoptosis. We …

Lipopolysaccharide (LPS) and gut ischemia/reperfusion (I/R) injury cause reversible liver
injury. Because nitric oxide (NO) can have both beneficial and deleterious effects in the …

Abstract mdash;: Hepatic Kupffer cells and pulmonary alveolar macrophages together
constitute a macrophage-axis involved in the regulation of regional and systemic …

An immunological liver injury model was established by injection of micro
lipopolysaccharide (LPS) into BCG (bacilli Calmette Guéin)-primed mice. It was found that …

Inflammatory stimulation of the liver induces nitric oxide (NO) biosynthesis and suppression
of detoxication. In this study the effect of NO biosynthesis on cytochrome P-450 (CYP) …

Objective To investigate the role and induced regulation of nitric oxide (NO) in rat
immunological hepatic injury, and the effect of selective inhibitor on induceble nitric oxide …

The role of nitric oxide (NO) in immunological liver injury in mice was studied. Moderate
increases in plasma NO levels and liver damage were seen after the injection of either …

Intravascular coagulation is involved in the development of certain types of liver injury,
including that induced by dimethylnitrosamine. Nitric oxide inhibits platelet aggregation and …

Sustained upregulation of inducible nitric oxide (NO) synthase in the liver after endotoxin
[lipopolysaccharide (LPS)] challenge may result in hepatocellular injury. We hypothesized …