Berberine is an isoquinoline alkaloid naturally produced by several types of plants.
Berberine has extensive pharmacological effects, such as anti-diabetic, anti-inflammatory …

The present study was conducted to evaluate the local antinociceptive actions of EA and the
possible involvement of l-arginine/NO/cGMP/K ATP channel pathway in this effect using …

The effect of modulators of the nitric oxide–cyclic GMP–protein kinase G–K+ channels
pathway on the local peripheral antinociceptive action induced by gabapentin was assessed …

Carbamazepine has been shown to exert analgesic effects in clinical and experimental pain
situation. This study was conducted to evaluate its potential peripheral antinociceptive …

Objectives The main purpose of this study was to assess the role of l-arginine/SNAP/NO/
cGMP/KATP channel pathway in analgesic effects of α-terpineol in mice. Methods Male …

As a promising flavonoid, naringenin has shown potential anti-inflammatory and antioxidant
properties mainly in inflammatory pain models by oral administration. Therefore, we …

The present study was conducted to evaluate the local antinociceptive actions of fluoxetine,
a selective serotonin reuptake inhibitor, and the possible involvement of the l …

Pamabrom is a diuretic that is effective in treating premenstrual syndrome and primary
dysmenorrhea. The aim of this study was to examine the effect of metformin and modulators …

Background Rutin is a bioflavonoid found in fruits, vegetables and plants used in traditional
medicine to alleviate pain. However, rutin's scientific evidence for the modulation of pain and …

The aim of this study was to examine if the peripheral antinociception of α-bisabolol involves
the participation of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) synthesis …