Clinically-meaningful improvements in therapy for unresectable NSCLC

S Katakura, S Murakami - Expert Review of Anticancer Therapy, 2022 - Taylor & Francis
Introduction The ideal management of patients with unresectable non-small-cell lung cancer
(NSCLC) is still developing. Unresectable NSCLC has a high mortality rate and poor …

Recent trends in the treatment of unresectable stage III non-small-cell lung cancer

G Makimoto, K Hotta, K Kiura - Respiratory Investigation, 2019 - Elsevier
Abstract Approximately 20–25% of non-small-cell lung cancer (NSCLC) is diagnosed when
the disease has progressed to clinical stage III. At this stage, and even if the cancer is …

Chemotherapy remains a cornerstone in the treatment of nonsmall cell lung cancer

R Pirker - Current opinion in oncology, 2020 - journals.lww.com
Chemotherapy remains a cornerstone in the treatment of nonsm... : Current Opinion in
Oncology Chemotherapy remains a cornerstone in the treatment of nonsmall cell lung cancer …

Giant steps and stumbling blocks

DF Heigener, M Reck - Nature Reviews Clinical Oncology, 2018 - nature.com
In 2017, major advances in the treatment of non-small-cell lung cancer (NSCLC) continued
to emanate from the fields of molecularly targeted therapy and immunotherapy. In the former …

Role of targeted therapy and immune checkpoint blockers in advanced non‐small cell lung cancer: a review

N Abdel Karim, K Kelly - The oncologist, 2019 - academic.oup.com
Advanced non‐small cell lung cancer (NSCLC) is a complex disease comprising
molecularly distinct tumor types, each with a unique biology that is becoming increasingly …

[HTML][HTML] Emerging evidence and treatment paradigm of non-small cell lung cancer

SYM Liu, MM Zheng, Y Pan, SY Liu, Y Li… - Journal of hematology & …, 2023 - Springer
Research on biomarker-driven therapy and immune check-point blockade in non-small cell
lung cancer (NSCLC) is rapidly evolving. The width and depth of clinical trials have also …

[HTML][HTML] Advanced-stage non–small cell lung cancer: advances in thoracic oncology 2018

J Remon, MJ Ahn, N Girard, M Johnson, DW Kim… - Journal of Thoracic …, 2019 - Elsevier
In 2018 research in the field of advanced NSCLCs led to an expanded reach and impact of
immune checkpoint inhibitors (ICIs) as part of a frontline treatment strategy, regardless of …

Non-small-cell lung cancer: what are the benefits and challenges of treating it with immune checkpoint inhibitors?

E Rassy, L Mezquita, J Remon, B Besse - Immunotherapy, 2019 - Future Medicine
Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape of advanced
non-small-cell lung cancer (NSCLC). It has improved the overall survival in the first-and …

[HTML][HTML] When to consider immune checkpoint inhibitors in oncogene-driven non-small cell lung cancer?

L Mhanna, N Guibert, J Milia, J Mazieres - Current treatment options in …, 2019 - Springer
Opinion statement Targeted therapies and more recently immune checkpoint inhibitors (ICI)
have transformed the treatment landscape of advanced NSCLC. Clinical trials investigating …

The end of nihilism: systemic therapy of advanced non–small cell lung cancer

V Ernani, CE Steuer, M Jahanzeb - Annual review of medicine, 2017 - annualreviews.org
Lung cancer is the leading cause of cancer death in the United States and many other parts
of the world. Non–small cell lung cancer (NSCLC) comprises 85–90% of lung cancers …