[PDF][PDF] SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux
A Mozzi, M Oldani, ME Forcella, C Vantaggiato… - Iscience, 2023 - cell.com
Coronaviruses encode a variable number of accessory proteins that are involved in host-
virus interaction, suppression of immune responses, or immune evasion. SARS-CoV-2 …
virus interaction, suppression of immune responses, or immune evasion. SARS-CoV-2 …
[HTML][HTML] The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
The SARS-CoV-2 genome encodes a multitude of accessory proteins. Using comparative
genomic approaches, an additional accessory protein, ORF3c, has been predicted to be …
genomic approaches, an additional accessory protein, ORF3c, has been predicted to be …
The Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis
S Lenhard, S Gerlich, A Khan, S Rödl… - Journal of Cell …, 2023 - rupress.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) expresses high
amounts of the protein Orf9b to target the mitochondrial outer membrane protein Tom70 …
amounts of the protein Orf9b to target the mitochondrial outer membrane protein Tom70 …
[HTML][HTML] Severe acute respiratory syndrome coronavirus-2 accessory proteins ORF3a and ORF7a modulate autophagic flux and Ca2+ homeostasis in yeast
JL Garrido-Huarte, J Fita-Torró, R Viana… - Frontiers in …, 2023 - frontiersin.org
Virus infection involves the manipulation of key host cell functions by specialized virulence
proteins. The Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) small …
proteins. The Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) small …
Binding of SARS-CoV-2 protein ORF9b to mitochondrial translocase TOM70 prevents its interaction with chaperone HSP90
The emergence of the COVID-19 pandemic, caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), remains a great threat to global health. ORF9b, an important …
coronavirus 2 (SARS-CoV-2), remains a great threat to global health. ORF9b, an important …
ORF9c and ORF10 as accessory proteins of SARS-CoV-2 in immune evasion
M Zandi - Nature Reviews Immunology, 2022 - nature.com
In a recent Perspective article in Nature Reviews Immunology (Wong, LY. R. & Perlman, S.
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related …
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related …
Endoplasmic reticulum-associated SARS-CoV-2 ORF3a elicits heightened cytopathic effects despite robust ER-associated degradation
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ORF3a protein plays a vital
role in viral pathogenesis and coronavirus disease 2019 (COVID-19). Like the spike protein …
role in viral pathogenesis and coronavirus disease 2019 (COVID-19). Like the spike protein …
[PDF][PDF] Some aspects of the life of SARS-CoV-2 ORF3a protein in mammalian cells
S Jiao, P Miranda, Y Li, D Maric, M Holmgren - Heliyon, 2023 - cell.com
The accessory protein ORF3a, from SARS-CoV-2, plays a critical role in viral infection and
pathogenesis. Here, we characterized ORF3a assembly, ion channel activity, subcellular …
pathogenesis. Here, we characterized ORF3a assembly, ion channel activity, subcellular …
ORF8/ORF8a: a difference between SARS-CoV-2 and SARS-CoV
M Zandi - European Respiratory Journal, 2022 - Eur Respiratory Soc
Recently in an editorial published as an “early view” paper in the European Respiratory
Journal, Hartsell et al.[1] reported that ORF8a has a role in SARS-CoV-2 infection. In figure …
Journal, Hartsell et al.[1] reported that ORF8a has a role in SARS-CoV-2 infection. In figure …
[HTML][HTML] SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease
The orphan gene of SARS-CoV-2, ORF10, is the least studied gene in the virus responsible
for the COVID-19 pandemic. Recent experimentation indicated ORF10 expression …
for the COVID-19 pandemic. Recent experimentation indicated ORF10 expression …
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