Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials
M Bafadhel, S Peterson, MA De Blas… - The Lancet …, 2018 - thelancet.com
Background The peripheral blood eosinophil count might help identify those patients with
chronic obstructive pulmonary disease (COPD) who will experience fewer exacerbations …
chronic obstructive pulmonary disease (COPD) who will experience fewer exacerbations …
Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the …
H Watz, K Tetzlaff, EFM Wouters, A Kirsten… - The lancet Respiratory …, 2016 - thelancet.com
Background Blood eosinophil counts might predict response to inhaled corticosteroids (ICS)
in patients with chronic obstructive pulmonary disease (COPD) and a history of …
in patients with chronic obstructive pulmonary disease (COPD) and a history of …
Blood eosinophils as a marker of response to inhaled corticosteroids in COPD
NC Barnes, R Sharma, S Lettis… - European Respiratory …, 2016 - Eur Respiratory Soc
Identification of a biomarker that predicts response to inhaled corticosteroids (ICS) would
help evaluate the risk/benefit profile of ICS in chronic obstructive pulmonary disease (COPD) …
help evaluate the risk/benefit profile of ICS in chronic obstructive pulmonary disease (COPD) …
Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials
D Singh, JA Wedzicha, S Siddiqui, A de la Hoz… - Respiratory …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterised by progressive
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
Blood eosinophil count, a marker of inhaled corticosteroid effectiveness in preventing COPD exacerbations in post-hoc RCT and observational studies: systematic …
TH Harries, V Rowland, CJ Corrigan, IJ Marshall… - Respiratory …, 2020 - Springer
Background Blood eosinophil count has been proposed as a predictor of response to
inhaled corticosteroid (ICS) in the prevention of acute exacerbations of COPD. An optimal …
inhaled corticosteroid (ICS) in the prevention of acute exacerbations of COPD. An optimal …
Blood eosinophil count and pneumonia risk in patients with chronic obstructive pulmonary disease: a patient-level meta-analysis
Background Inhaled corticosteroids are important in the management of chronic obstructive
pulmonary disease (COPD), but can slightly increase the risk of pneumonia in patients with …
pulmonary disease (COPD), but can slightly increase the risk of pneumonia in patients with …
Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trial
M Bafadhel, S McKenna, S Terry, V Mistry… - American journal of …, 2012 - atsjournals.org
Rationale: Exacerbations of chronic obstructive pulmonary disease (COPD) and responses
to treatment are heterogeneous. Objectives: Investigate the usefulness of blood eosinophils …
to treatment are heterogeneous. Objectives: Investigate the usefulness of blood eosinophils …
Blood eosinophils and inhaled corticosteroids in patients with COPD: systematic review and meta-analysis
SL Cheng - International journal of chronic obstructive pulmonary …, 2018 - Taylor & Francis
Background COPD is a highly heterogeneous disease. Potential biomarkers to identify
patients with COPD who will derive the greatest benefit from inhaled corticosteroid (ICS) …
patients with COPD who will derive the greatest benefit from inhaled corticosteroid (ICS) …
Blood eosinophil guided prednisolone therapy for exacerbations of COPD: a further analysis
M Bafadhel, L Davies, PMA Calverley… - European …, 2014 - Eur Respiratory Soc
Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with
significant morbidity and mortality [ 1]. Current guidelines advocate the use of systemic …
significant morbidity and mortality [ 1]. Current guidelines advocate the use of systemic …
Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease …
S Pascoe, N Locantore, MT Dransfield… - The lancet Respiratory …, 2015 - thelancet.com
Background The short-term benefits of inhaled corticosteroids for patients with chronic
obstructive pulmonary disease (COPD) are greater in patients with evidence of eosinophilic …
obstructive pulmonary disease (COPD) are greater in patients with evidence of eosinophilic …