Sterile intra-amniotic inflammation is commonly observed in patients with spontaneous
preterm labor, a syndrome that commonly precedes preterm birth, the leading cause of …

Intra-amniotic inflammation is strongly associated with spontaneous preterm labor and birth,
the leading cause of perinatal mortality and morbidity worldwide. Previous studies have …

Preterm birth remains the leading cause of neonatal morbidity and mortality worldwide. A
substantial number of spontaneous preterm births occur in the context of sterile intra …

Sterile intra-amniotic inflammation is a clinical condition frequently observed in women with
preterm labor and birth, the leading cause of neonatal morbidity and mortality worldwide …

Inflammasomes are cytoplasmic multiprotein complexes that coordinate inflammatory
responses, including those that take place during pregnancy. Inflammasomes and their …

Fetal growth restriction (FGR) is commonly associated with placental insufficiency and
inflammation. Nonetheless, the role played by inflammasomes in the pathogenesis of FGR is …

Reproduction involves tightly regulated series of events and the immune system is involved
in an array of reproductive processes. Disruption of well-controlled immune functions leads …

The NOD-like receptor protein 3 (NLRP3) inflammasome is a key regulator of the host's
immune response, and many immune and metabolic disorders are linked to its activation …

Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. One of
every 4 preterm neonates is born to a mother with intra-amniotic inflammation driven by …

Pre-eclampsia is associated with increased levels of cholesterol and uric acid and an
inflamed placenta expressing danger-sensing pattern recognition receptors (PRRs) …