Autophagy is a complex degradative process by which eukaryotic cells capture cytoplasmic
components for subsequent degradation through lysosomal hydrolases. Although this …

Autophagy is a self-degradative process important for balancing cellular homeostasis at
critical times in development and/or in response to nutrient stress. This is particularly …

About 20% of total cancer cases are associated to infections. To date, seven human viruses
have been directly linked to cancer development: high-risk human papillomaviruses …

Autophagy is an intracellular degradation pathway for long-lived proteins and organelles.
This process is activated above basal levels upon cell intrinsic or environmental stress and …

Autophagy is a fundamental catabolic process essential for the maintenance of cellular and
tissue homeostasis, as well as directly contributing to the control of invading pathogens …

Maintenance of protein homeostasis and organelle integrity and function is critical for
cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates …

Autophagy is a lysosomal degradation process crucial for adaptation to stress and cellular
homeostasis. In cancer, autophagy has been demonstrated to serve multifaceted roles in …

Autophagy plays a complex impact role in tumor initiation and development. It serves as a
double-edged sword by supporting cell survival in certain situations while also triggering …

Evolutionarily conserved across eukaryotic cells, macroautophagy (herein autophagy) is an
intracellular catabolic degradative process targeting damaged and superfluous cellular …

Oncolytic viruses have attracted attention as a promising strategy in cancer therapy owing to
their ability to selectively infect and kill tumor cells, without affecting healthy cells. They also …