Selenoproteins are proteins containing selenium in the form of the 21st amino acid,
selenocysteine. Members of this protein family have many diverse functions, but their …

Since the recent discovery of selenocysteine as the 21st amino acid in protein, the field of
selenium biology has rapidly expanded. Twelve mammalian selenoproteins have been …

Selenium is an essential trace element for which both beneficial and toxic effects in human
health have been described. It is now clear that the importance of having adequate amounts …

Selenium is an essential micronutrient with important functions in human health and
relevance to several pathophysiological conditions. The biological effects of selenium are …

Selenium is an essential micronutrient in mammals, but is also recognized as toxic in
excess. It is a non-metal with properties that are intermediate between the chalcogen …

The beneficial role of the trace element selenium (Se) in human health has been known for
several decades and is attributed both to low-molecular-weight Se compounds and to its …

In the last few decades, the importance of selenium in human health has been the subject of
numerous studies. It is believed that the physiological effects of selenium occur mainly …

Mammalian selenium-containing proteins identified thus far contain selenium in the form of a
selenocysteine residue encoded by UGA. These proteins lack common amino acid …

Biological functions of selenium are exerted by selenoproteins that contain selenocysteine
in their primary structure. Selenocysteine is synthesized and inserted into proteins …

Several decades after the discovery of selenium as an essential trace element in vertebrates
approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the …