Revisiting doxycycline in pregnancy and early childhood–time to rebuild its reputation?

R Cross, C Ling, NPJ Day, R McGready… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Doxycycline is highly effective, inexpensive with a broad therapeutic spectrum
and exceptional bioavailability. However these benefits have been overshadowed by its …

Safety and efficacy review of doxycycline

NE Holmes, PGP Charles - Clinical Medicine. Therapeutics, 2009 - journals.sagepub.com
Doxycycline is a member of the tetracycline class of antibiotics and has been used clinically
for more than 40 years. It is a well-tolerated drug that is bacteriostatic and acts via the …

The use and safety of doxycycline hyclate and other second-generation tetracyclines

B Sloan, N Scheinfeld - Expert opinion on drug safety, 2008 - Taylor & Francis
Tetracyclines have long been used to treat a wide variety of medical conditions, especially in
the field of dermatology. Unfortunately, safety concerns, especially gastrointestinal (GI), have …

A population-based case-control teratologic study of oral oxytetracycline treatment during pregnancy

AE Czeizel, M Rockenbauer - … Journal of Obstetrics & Gynecology and …, 2000 - Elsevier
Objective: To study human teratogenic potential of oral oxytetracycline treatment during
pregnancy. Materials and Methods: The pair analysis of cases with congenital abnormalities …

Teratogenic study of doxycycline

AE Czeizel, M Rockenbauer - Obstetrics & Gynecology, 1997 - Elsevier
OBJECTIVE: To study the human teratogenic risk of doxycycline treatment during
pregnancy. METHODS: Paired analysis of cases with congenital abnormalities and matched …

Safety of doxycycline and minocycline: a systematic review

K Smith, JJ Leyden - Clinical therapeutics, 2005 - Elsevier
OBJECTIVE:: The goal of this review was to summarize the available literature covering the
safety profiles of oral doxycycline and minocycline. METHODS:: Scientific literature …

A systematic review of the impacts of oral tetracycline class antibiotics on antimicrobial resistance in normal human flora

R Truong, V Tang, T Grennan… - JAC-antimicrobial …, 2022 - academic.oup.com
Objectives There is interest in doxycycline as prophylaxis against sexually transmitted
infections (STIs), but concern about antimicrobial resistance (AMR). We conducted a …

[HTML][HTML] Antibiotic use and misuse during pregnancy and delivery: benefits and risks

B Martinez de Tejada - … journal of environmental research and public …, 2014 - mdpi.com
Although pregnancy is considered as a physiological state, most pregnant women in
developed countries receive multiple medications to prevent maternal or neonatal …

Doxycycline in the management of sexually transmitted infections

H Peyriere, A Makinson, H Marchandin… - Journal of …, 2018 - academic.oup.com
Doxycycline is a second-generation tetracycline, available worldwide for half a century. It is
an inexpensive broad-spectrum antimicrobial agent largely used in the management of …

Doxycycline

BA Cunha, CM Sibley, AM Ristuccia - Therapeutic drug monitoring, 1982 - journals.lww.com
The chemistry, mode of action, antimicrobial activity, pharmco kinetics, and therapeutic
efficacy of doxycycline are reviewed. Doxycycline displays excellent activity against gram …