Background Inflammasomes are involved in diverse inflammatory diseases. Previous study
reported that the neurotransmitter dopamine inhibited NLRP3 inflammasome activation via …

Background and Purpose—Inflammatory injury plays a critical role in intracerebral
hemorrhage (ICH)–induced secondary brain injury. Recently, dopamine D2 receptor …

Inflammasomes are involved in diverse inflammatory diseases, so the activation of
inflammasomes needs to be tightly controlled to prevent excessive inflammation. However …

The abnormally high nucleotide-binding oligomerization domain (NOD)-like receptor family
pyrin domain containing 3 (NLRP3) inflammasome activity is a typical characteristic of …

Intracerebral hemorrhage (ICH) is the most fatal subtype of stroke; there is still a lack of
effective treatment. Microglia are a major component of the innate immune system, and they …

Astrocytes are involved in the neuroinflammation of neurodegenerative diseases, such as
Parkinson's disease (PD). Among the numerous inflammatory cytokines, interleukin-1β (IL …

Background Nod-like receptor protein 3 (NLRP3) inflammasome is a crucial factor in
mediating inflammatory responses after cerebral ischemia/reperfusion (I/R), but the cellular …

Background The NOD-like receptor family pyrin domain-containing 3 (NLRP3)
inflammasome is an important mediator of neuroinflammatory responses that regulates …

Hemorrhagic stroke is a devastating disease with high morbidity and mortality. There is still a
lack of effective therapeutic approach. The recent studies have shown that the innate …

Study Design. A randomized experimental study. Objective. The aim of this study was to
investigate the therapeutic efficacy and molecular mechanisms of dopamine D1 receptor …