Eukaryotic cells use clathrin-mediated endocytosis to take up a large range of extracellular
cargo. During endocytosis, a clathrin coat forms on the plasma membrane, but it remains …

Although essential for many cellular processes, the sequence of structural and molecular
events during clathrin-mediated endocytosis remains elusive. While it was long believed that …

Clathrin-mediated endocytosis (CME) internalizes plasma membrane by reshaping small
regions of the cell surface into spherical vesicles. The key mechanistic question of how coat …

Clathrin-mediated endocytosis is the primary pathway for receptor and cargo internalization
in eukaryotic cells. It is characterized by a polyhedral clathrin lattice that coats budding …

Clathrin polymerization and changes in plasma membrane architecture are necessary steps
in forming vesicles to internalize cargo during clathrin-mediated endocytosis (CME) …

Sculpting a flat patch of membrane into an endocytic vesicle requires curvature generation
on the cell surface, which is the primary function of the endocytosis machinery. Using super …

Clathrin-mediated endocytosis (CME) is the primary mechanism eukaryotic cells use to
internalize material. New imaging tools are revealing the nanoscale structural dynamics of …

Cellular activity depends to a large extent on membrane bilayer dynamics. Many processes,
such as organelle biogenesis and vesicular transport, rely on alterations in membrane …

Clathrin-mediated endocytosis involves the coordinated assembly of clathrin cages around
membrane indentations, necessitating fluid-like reorganization followed by solid-like …

Clathrin-mediated endocytosis is an essential cellular mechanism by which all eukaryotic
cells regulate their plasma membrane composition to control processes ranging from cell …